Success Metrics

Clinical Success Rate
96.4%

Based on 27 completed trials

Completion Rate
96%(27/28)
Active Trials
3(8%)
Results Posted
26%(7 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_1
6
17%
Ph phase_3
5
14%
Ph not_applicable
12
33%
Ph phase_2
9
25%
Ph phase_4
4
11%

Phase Distribution

6

Early Stage

9

Mid Stage

9

Late Stage

Phase Distribution36 total trials
Phase 1Safety & dosage
6(16.7%)
Phase 2Efficacy & side effects
9(25.0%)
Phase 3Large-scale testing
5(13.9%)
Phase 4Post-market surveillance
4(11.1%)
N/ANon-phased studies
12(33.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

96.4%

27 of 28 finished

Non-Completion Rate

3.6%

1 ended early

Currently Active

3

trials recruiting

Total Trials

36

all time

Status Distribution
Active(5)
Completed(27)
Terminated(1)
Other(3)

Detailed Status

Completed27
unknown3
Recruiting2
Active, not recruiting1
Terminated1
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
36
Active
3
Success Rate
96.4%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (16.7%)
Phase 29 (25.0%)
Phase 35 (13.9%)
Phase 44 (11.1%)
N/A12 (33.3%)

Trials by Status

active_not_recruiting13%
recruiting26%
terminated13%
enrolling_by_invitation13%
not_yet_recruiting13%
unknown38%
completed2775%

Recent Activity

Clinical Trials (36)

Showing 20 of 36 trialsScroll for more
NCT02910531Phase 2

Lipoic Acid Supplement for Cystine Stone

Completed
NCT07456176Phase 3

Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Not Yet Recruiting
NCT04042935Phase 1

Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC

Completed
NCT06286098Phase 3

Alpha Lipoic Acid in Pediatrics on Hemodialysis

Enrolling By Invitation
NCT07381361Not Applicable

Photobiomodulation Therapy vs. Alpha-Lipoic Acid in Burning Mouth Syndrome Treatment

Active Not Recruiting
NCT07256119Not Applicable

Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients

Recruiting
NCT06703593Phase 2

Prevention of Doxorubicin-induced Cardiotoxicity in Breast Cancer Patients

Completed
NCT06787781Not Applicable

Metabolic and Clinical Effect of Alpha-lipoic Acid Administration in Schizophrenic Subjects

Completed
NCT06418347Phase 3

Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females

Recruiting
NCT06131918Phase 2

Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy

Completed
NCT06195137Not Applicable

Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)

Completed
NCT05369793Phase 3

Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy

Completed
NCT05266794Phase 4

A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients

Completed
NCT04322240Not Applicable

Alpha Lipoic Acid and Diabetes Mellitus: Potential Effects on Peripheral Neuropathy

Completed
NCT03612037Not Applicable

Impact of Alpha-Lipoic Acid Ingestion on Glucose Tolerance in Subjects With Pre-Diabetes

Completed
NCT02613572Phase 1

Alpha Lipoic Acid in Geographic Atrophy

Completed
NCT04041167Phase 3

Impact of Lipoic Acid Use on Stroke Outcome After Reperfusion Therapy in Patients With Diabetes (IMPORTANT)

Unknown
NCT03493841Phase 1

Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis

Completed
NCT01880372Not Applicable

The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy

Terminated
NCT03589690Not Applicable

Alpha Lipoic Acid Supplementation and Metabolic Syndrome

Unknown

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
36