Success Metrics

Clinical Success Rate
91.7%

Based on 33 completed trials

Completion Rate
92%(33/36)
Active Trials
1(3%)
Results Posted
85%(28 trials)
Terminated
3(8%)

Phase Distribution

Ph phase_3
17
43%
Ph not_applicable
1
3%
Ph phase_4
7
18%
Ph phase_2
4
10%
Ph phase_1
5
13%

Phase Distribution

5

Early Stage

4

Mid Stage

24

Late Stage

Phase Distribution34 total trials
Phase 1Safety & dosage
5(14.7%)
Phase 2Efficacy & side effects
4(11.8%)
Phase 3Large-scale testing
17(50.0%)
Phase 4Post-market surveillance
7(20.6%)
N/ANon-phased studies
1(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

89.2%

33 of 37 finished

Non-Completion Rate

10.8%

4 ended early

Currently Active

1

trials recruiting

Total Trials

40

all time

Status Distribution
Active(1)
Completed(33)
Terminated(4)
Other(2)

Detailed Status

Completed33
Terminated3
unknown2
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
40
Active
1
Success Rate
91.7%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (14.7%)
Phase 24 (11.8%)
Phase 317 (50.0%)
Phase 47 (20.6%)
N/A1 (2.9%)

Trials by Status

recruiting13%
completed3383%
unknown25%
terminated38%
withdrawn13%

Recent Activity

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more
NCT03499704Phase 4

A Study to Evaluate the Effect of add-on Pioglitazone or Dapagliflozin in Participants With Type 2 Diabetes Mellitus Inadequately Controlled by DPP-4 Inhibitor and Metformin Therapy

Completed
NCT07093476Phase 3

Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin

Recruiting
NCT03231709Phase 4

Treatment Preference for Weekly Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Daily DPP-4 Inhibitors in Participants With Type 2 Diabetes Mellitus

Completed
NCT02771093Phase 4

An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes Mellitus

Completed
NCT02068443Phase 3

Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise Therapy

Completed
NCT05782192Phase 3

SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Completed
NCT03794336Phase 4

Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive

Completed
NCT01964963

Alogliptin Tablets Special Drug Use Surveillance: Mild Type 2 Diabetes Mellitus

Completed
NCT01945216

Alogliptin Tablets Special Drug Use Surveillance "Type 2 Diabetes Mellitus: Monotherapy/Combination Therapy With α-GI"

Completed
NCT02221284

Alogliptin Tablets Specified Drug-use Survey "Type 2 Diabetic Patients Receiving Combination Therapy With a Hypoglycemic Agent (e.g., Insulin Preparations or Rapid-acting Insulin Secretagogues)"

Completed
NCT03501277Phase 1

A Study to Determine the Bioequivalence of Alogliptin and Pioglitazone When Administered as Individual Tablets and as Fixed-Dose Combination (FDC)-SYR-322-4833 BL Tablets to Healthy Russian Participants

Completed
NCT02763007Phase 4

An Extension Study of PEAK Trial

Terminated
NCT02989649

Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

Terminated
NCT02231021Phase 4

The Practical Evidence of Antidiabetic Combination Therapy in Korea

Completed
NCT03042325Phase 4

Safety and Efficacy of Alogliptin in Indian Participants With Type 2 Diabetes Mellitus

Withdrawn
NCT01664624Phase 1

Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes

Completed
NCT01890122Phase 3

Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

Completed
NCT02508168Phase 1

Phase 1 Bioavailability Study of SYR-322MET

Completed
NCT01945242

Alogliptin Tablets Special Drug Use Surveillance "Type 2 Diabetes Mellitus: Combination Therapy With Thiazolidinediones"

Completed
NCT00957268Phase 1

Pharmacokinetics, Pharmacodynamics, and Safety of Alogliptin in Children, Adolescents and Adults With Type 2 Diabetes Mellitus

Completed

Drug Details

Intervention Type
DRUG
Total Trials
40