Success Metrics

Active Trials
10(31%)

Phase Distribution

Ph phase_3
11
34%
Ph not_applicable
2
6%
Ph phase_2
16
50%
Ph phase_1
3
9%

Phase Distribution

3

Early Stage

16

Mid Stage

11

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
3(9.4%)
Phase 2Efficacy & side effects
16(50.0%)
Phase 3Large-scale testing
11(34.4%)
N/ANon-phased studies
2(6.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

10

trials recruiting

Total Trials

32

all time

Status Distribution
Active(13)
Other(19)

Detailed Status

unknown19
Recruiting6
Active, not recruiting4
Not yet recruiting2
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
32
Active
10
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 13 (9.4%)
Phase 216 (50.0%)
Phase 311 (34.4%)
N/A2 (6.3%)

Trials by Status

not_yet_recruiting26%
active_not_recruiting413%
enrolling_by_invitation13%
unknown1959%
recruiting619%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT04841811Phase 3

MDT-bridged Radical Therapy After Aumolertinib Introduction and Followed by MRD-guided Maintained Therapy for EGFR-mutated Unresectable Stage III NSCLC (APPROACH/CTONG2101)

Active Not Recruiting
NCT06300424Phase 2

Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC

Active Not Recruiting
NCT06951464Phase 2

A Study of BL-B01D1 and Almonertinib in Patients With Resectable EGFR+ Stage II-IIIB NSCLC

Recruiting
NCT06947811Phase 1

A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations

Recruiting
NCT04687241Phase 3

Almonertinib Versus Placebo as Adjuvant Therapy in Resected Stage II-IIIB Non-Small Cell Lung Cancer With EGFR-sensitive Mutations

Active Not Recruiting
NCT06463171Phase 2

Phase II Trial of Almonertinib Plus Lastet for EGFR+ Non-small Cell Lung Cancer

Not Yet Recruiting
NCT04808752Phase 2

Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases

Active Not Recruiting
NCT04354961Phase 2

Almonertinib as First-line Treatment in Patients With EGFR+ Positive Pulmonary Adenosquamous Carcinoma or Combined Adenocarcinoma and Squamous Cell Carcinoma

Unknown
NCT06043973Phase 3

Almonertinib Combined With Anlotinib as First-line Treatment for Advanced Non-small Cell Lung Cance

Recruiting
NCT05994339Phase 2

Radiotherapy Combined With Almonertinib for Stage III EGFR-Mutated Lung Cancer

Unknown
NCT05826483Phase 1

Almonertinib in the First-line Treatment of Patients of NSCLC With Poor Performance Status

Unknown
NCT05800223Phase 3

Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer

Recruiting
NCT05768490Phase 3

Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases

Recruiting
NCT05662813Phase 2

Almonertinib Therapy in Patients With Abnormal Liver Function After EGFR-TKI Treatment, or Almonertinib First-line Therapy in Patients With Basic Hepatopathy

Unknown
NCT05503888Phase 1

Phase Ib/II Study of Almonertinib Combined With SHR-1701 in the Treatment of Relapsed or Advanced Non-small Cell Lung Cancer

Not Yet Recruiting
NCT04951635Phase 3

A Phase III Study to Assess the Effects of Almonertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer

Recruiting
NCT04762459Phase 3

Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection

Enrolling By Invitation
NCT04778800Not Applicable

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

Unknown
NCT04952168Phase 2

Combination of Almonertinib and Concurrent Chemoradiotherapy in Unresectable Stage III NSCLC

Unknown
NCT04951648Phase 3

A Phase III Study to Assess the Efficacy and Safety of Almonertinib Versus Platinum-based Chemotherapy as First-line Therapy in Patients With Locally Advanced or Metastatic NSCLC Harbouring Uncommon EGFR Mutation

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
32