Success Metrics

Clinical Success Rate
81.6%

Based on 80 completed trials

Completion Rate
82%(80/98)
Active Trials
1(1%)
Results Posted
64%(51 trials)
Terminated
18(16%)

Phase Distribution

Ph phase_2
11
10%
Ph phase_1
10
9%
Ph phase_3
42
37%
Ph phase_4
41
36%
Ph not_applicable
9
8%

Phase Distribution

10

Early Stage

11

Mid Stage

83

Late Stage

Phase Distribution113 total trials
Phase 1Safety & dosage
10(8.8%)
Phase 2Efficacy & side effects
11(9.7%)
Phase 3Large-scale testing
42(37.2%)
Phase 4Post-market surveillance
41(36.3%)
N/ANon-phased studies
9(8.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.4%

80 of 102 finished

Non-Completion Rate

21.6%

22 ended early

Currently Active

1

trials recruiting

Total Trials

114

all time

Status Distribution
Active(1)
Completed(80)
Terminated(22)
Other(11)

Detailed Status

Completed80
Terminated18
unknown11
Withdrawn4
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
114
Active
1
Success Rate
81.6%
Most Advanced
Phase 4

Trials by Phase

Phase 110 (8.8%)
Phase 211 (9.7%)
Phase 342 (37.2%)
Phase 441 (36.3%)
N/A9 (8.0%)

Trials by Status

recruiting11%
unknown1110%
withdrawn44%
completed8070%
terminated1816%

Recent Activity

1 active trials
Showing 5 of 114
recruitingphase_2

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

NCT04183101
completedphase_4

Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia

NCT06718062
completedphase_3

A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension

NCT00667719
completedphase_1

Effect of Light Meal on Pharmacokinetic and Pharmacodynamics of Aliskiren in Patients With Mild to Moderate Hypertension

NCT00933920
completedphase_4

Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate Hypertension

NCT00765947
View all 114 trials

Clinical Trials (114)

Showing 20 of 114 trialsScroll for more
NCT04183101Phase 2

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

Recruiting
NCT06718062Phase 4

Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia

Completed
NCT00667719Phase 3

A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension

Completed
NCT00933920Phase 1

Effect of Light Meal on Pharmacokinetic and Pharmacodynamics of Aliskiren in Patients With Mild to Moderate Hypertension

Completed
NCT00765947Phase 4

Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate Hypertension

Completed
NCT01519635Phase 4

Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With Hypertension

Completed
NCT00219102Phase 3

A Clinical Study to Evaluate Safety & Efficacy of the Combination of Aliskiren, Valsartan & Hydrochlorothiazide in Diabetic Hypertensive Nonresponder Patients

Completed
NCT00982033Phase 4

Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction

Completed
NCT01235910Phase 4

Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac Transplantation

Terminated
NCT00974922Phase 4

Vitamin D Deficiency in Patients With Hypertension

Terminated
NCT01461499Phase 4

Shiga Microalbuminuria Reduction Trial-2

Completed
NCT01252238Not Applicable

Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance

Terminated
NCT01318395Phase 3

Aliskiren on Retinal Vasculature Treatment Study

Completed
NCT00818779Phase 4

Direct Renin Inhibition Effects on Atherosclerotic Biomarkers

Completed
NCT00223717Phase 1

Treatment of Supine Hypertension in Autonomic Failure

Completed
NCT00994253Phase 4

Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics

Withdrawn
NCT01715207Phase 3

Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS

Completed
NCT00219076Phase 3

A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Amlodipine in Hypertensive Non Responders Patients

Completed
NCT00219024Phase 3

Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.

Completed
NCT00219180Phase 3

Clinical Study to Evaluate Efficacy and Safety of Aliskiren (150mg & 300mg) Administered Alone and in Combo With Valsartan (160mg and 320mg) in Patients With High Blood Pressure

Completed

Drug Details

Intervention Type
DRUG
Total Trials
114