Success Metrics

Clinical Success Rate
85.7%

Based on 12 completed trials

Completion Rate
86%(12/14)
Active Trials
0(0%)
Results Posted
83%(10 trials)
Terminated
2(13%)

Phase Distribution

Ph phase_4
9
56%
Ph phase_2
1
6%
Ph phase_3
2
13%

Phase Distribution

0

Early Stage

1

Mid Stage

11

Late Stage

Phase Distribution12 total trials
Phase 2Efficacy & side effects
1(8.3%)
Phase 3Large-scale testing
2(16.7%)
Phase 4Post-market surveillance
9(75.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.7%

12 of 14 finished

Non-Completion Rate

14.3%

2 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Active(1)
Completed(12)
Terminated(2)
Other(1)

Detailed Status

Completed12
Terminated2
Not yet recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Phase 21 (8.3%)
Phase 32 (16.7%)
Phase 49 (75.0%)

Trials by Status

terminated213%
completed1275%
not_yet_recruiting16%
unknown16%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT03729362Phase 3

A Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Disease

Completed
NCT04676373Phase 4

Study to Evaluate Efficacy and Safety in Chinese Patients With Late Onset Pompe Disease With Alglucosidase Alfa Treatmen

Completed
NCT00566878

Pompe Lactation Sub-Registry

Completed
NCT00486889Phase 4

Growth and Development Study of Alglucosidase Alfa

Completed
NCT01410890Phase 4

Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease

Completed
NCT05017402

Higher Dose of Alglucosidase Alpha for Pompe Disease

Not Yet Recruiting
NCT01710813

Alglucosidase Alfa Pompe Safety Sub-Registry

Completed
NCT01597596Phase 4

A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Patients With Infantile-Onset Pompe Disease

Terminated
NCT01526785Phase 4

A Study to Evaluate the Efficacy and Safety of Alglucosidase Alfa Produced at the 4000 L Scale for Pompe Disease

Terminated
NCT00158600Phase 3

A Placebo-Controlled Study of Safety and Effectiveness of Myozyme (Alglucosidase Alfa) in Patients With Late-Onset Pompe Disease

Completed
NCT01288027Phase 4

Exploratory Muscle Biopsy Assessment Study in Patients With Late-Onset Pompe Disease Treated With Alglucosidase Alfa

Completed
NCT00701129Phase 4

An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease

Completed
NCT00483379Phase 4

High Dose or High Dose Frequency Study of Alglucosidase Alfa

Completed
NCT00455195Phase 4

Late-Onset Treatment Study Extension Protocol

Completed
NCT00074919

Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Infantile-onset Pompe Disease

Unknown
NCT00051935Phase 2

A Study of the Safety and Pharmacokinetics of rhGAA in Siblings With Glycogen Storage Disease Type II

Completed

All 16 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
16