Aldesleukin
Aldesleukin is a biological therapy with 317 clinical trials. Currently 27 active trials ongoing. Historical success rate of 75.9%.
Success Metrics
Based on 189 completed trials
Phase Distribution
Phase Distribution
147
Early Stage
132
Mid Stage
26
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
72.1%
189 of 262 finished
27.9%
73 ended early
27
trials recruiting
317
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer
A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
Clinical Trials (317)
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer
A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC
Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
E7 TCR T Cells for Human Papillomavirus-Associated Cancers
Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering
CISH Inactivated TILs in the Treatment of NSCLC
A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies.
Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 317