Success Metrics

Clinical Success Rate
73.1%

Based on 19 completed trials

Completion Rate
73%(19/26)
Active Trials
2(7%)
Results Posted
105%(20 trials)
Terminated
7(24%)

Phase Distribution

Ph phase_1
9
31%
Ph phase_2
20
69%

Phase Distribution

9

Early Stage

20

Mid Stage

0

Late Stage

Phase Distribution29 total trials
Phase 1Safety & dosage
9(31.0%)
Phase 2Efficacy & side effects
20(69.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

70.4%

19 of 27 finished

Non-Completion Rate

29.6%

8 ended early

Currently Active

2

trials recruiting

Total Trials

29

all time

Status Distribution
Active(2)
Completed(19)
Terminated(8)

Detailed Status

Completed19
Terminated7
Active, not recruiting2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
29
Active
2
Success Rate
73.1%
Most Advanced
Phase 2

Trials by Phase

Phase 19 (31.0%)
Phase 220 (69.0%)

Trials by Status

completed1966%
terminated724%
active_not_recruiting27%
withdrawn13%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT01251861Phase 2

Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate Cancer

Active Not Recruiting
NCT01480154Phase 1

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

Active Not Recruiting
NCT01307631Phase 2

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer

Completed
NCT01258998Phase 2

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

Completed
NCT01239342Phase 2

Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer

Terminated
NCT01802320Phase 2

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Completed
NCT01604772Phase 2

Akt Inhibitor MK2206 in Treating Patients With Progressive, Recurrent, or Metastatic Adenoid Cyst Carcinoma

Completed
NCT01277757Phase 2

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

Completed
NCT01253447Phase 2

AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Completed
NCT01344031Phase 1

MK2206 in Combination With Anastrozole, Fulvestrant, or Anastrozole and Fulvestrant in Treating Postmenopausal Women With Metastatic Breast Cancer

Completed
NCT01776008Phase 2

Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer

Terminated
NCT01349933Phase 2

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Completed
NCT01481129Phase 2

Akt Inhibitor MK2206 in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Completed
NCT01369849Phase 1

Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Completed
NCT01319539Phase 2

MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer

Terminated
NCT01263145Phase 1

MK2206 and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Metastatic Breast Cancer

Completed
NCT01783171Phase 1

Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery

Completed
NCT01294306Phase 2

MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy

Completed
NCT01283035Phase 2

A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer

Completed
NCT01425879Phase 2

MK2206 in Treating Patients With Advanced Refractory Biliary Cancer That Cannot Be Removed by Surgery

Completed

Drug Details

Intervention Type
DRUG
Total Trials
29