Success Metrics

Clinical Success Rate
87.5%

Based on 7 completed trials

Completion Rate
88%(7/8)
Active Trials
23(66%)
Results Posted
0%(0 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_4
1
3%
Ph phase_2
15
43%
Ph phase_1
15
43%
Ph phase_3
4
11%

Phase Distribution

15

Early Stage

15

Mid Stage

5

Late Stage

Phase Distribution35 total trials
Phase 1Safety & dosage
15(42.9%)
Phase 2Efficacy & side effects
15(42.9%)
Phase 3Large-scale testing
4(11.4%)
Phase 4Post-market surveillance
1(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.5%

7 of 8 finished

Non-Completion Rate

12.5%

1 ended early

Currently Active

23

trials recruiting

Total Trials

35

all time

Status Distribution
Active(27)
Completed(7)
Terminated(1)

Detailed Status

Recruiting15
Active, not recruiting8
Completed7
Not yet recruiting4
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
23
Success Rate
87.5%
Most Advanced
Phase 4

Trials by Phase

Phase 115 (42.9%)
Phase 215 (42.9%)
Phase 34 (11.4%)
Phase 41 (2.9%)

Trials by Status

not_yet_recruiting411%
active_not_recruiting823%
completed720%
terminated13%
recruiting1543%

Recent Activity

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT05689853Phase 1

Study of AK119 Combined With AK112 in Patients With Advanced Solid Tumors

Recruiting
NCT06767527Phase 3

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Recruiting
NCT05227664Phase 2

A Study of AK117/AK112 in Metastatic Triple-Negative Breast Cancer

Active Not Recruiting
NCT07052253Phase 2

A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.

Recruiting
NCT05499390Phase 3

AK112 in Advanced Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05904379Phase 1

AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer

Active Not Recruiting
NCT05636267Phase 1

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

Terminated
NCT05229497Phase 1

A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors

Active Not Recruiting
NCT07010263Phase 3

A Study of AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation Therapy

Recruiting
NCT05247684Phase 2

AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC

Active Not Recruiting
NCT06530251Phase 1

A Study of AK112 in Patients With Advanced Hepatocellular Carcinoma (HCC)

Recruiting
NCT06951503Phase 3

AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer

Recruiting
NCT05432492Phase 2

A Study of AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC)

Completed
NCT05846867Phase 1

A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer

Active Not Recruiting
NCT05214482Phase 1

A Study of AK112 in Advanced Malignant Tumors

Completed
NCT07114315Phase 2

A Study of AK130 in Combination With AK112 for the Treatment of Advanced Pancreatic Cancer

Recruiting
NCT06938321Phase 1

A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer

Recruiting
NCT04900363Phase 1

A Trial of AK112 (PD-1/VEGF Bispecific Antibody) in Patients With NSCLC

Completed
NCT04736823Phase 2

A Trial of AK112 (PD1/VEGF Bispecific) in Combination With Chemotherapy in Patients With NSCLC

Active Not Recruiting
NCT07385001Phase 1

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
35