Success Metrics

Clinical Success Rate
69.2%

Based on 18 completed trials

Completion Rate
69%(18/26)
Active Trials
0(0%)
Results Posted
133%(24 trials)
Terminated
8(29%)

Phase Distribution

Ph phase_2
14
50%
Ph phase_3
10
36%
Ph phase_1
4
14%

Phase Distribution

4

Early Stage

14

Mid Stage

10

Late Stage

Phase Distribution28 total trials
Phase 1Safety & dosage
4(14.3%)
Phase 2Efficacy & side effects
14(50.0%)
Phase 3Large-scale testing
10(35.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

64.3%

18 of 28 finished

Non-Completion Rate

35.7%

10 ended early

Currently Active

0

trials recruiting

Total Trials

28

all time

Status Distribution
Completed(18)
Terminated(10)

Detailed Status

Completed18
Terminated8
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
28
Active
0
Success Rate
69.2%
Most Advanced
Phase 3

Trials by Phase

Phase 14 (14.3%)
Phase 214 (50.0%)
Phase 310 (35.7%)

Trials by Status

terminated829%
completed1864%
withdrawn27%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT04711902Phase 3

Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo.

Completed
NCT01364389Phase 2

A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica

Terminated
NCT03136861Phase 3

SKIPPAIN - Speed of Onset of SecuKinumab-Induced Relief From Pain in Patients With AxIal SpoNdyloarthritis

Completed
NCT01009281Phase 2

An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease

Terminated
NCT02607774Phase 1

Investigate Effect of Secukinumab on the PK of Midazolam in Patients With Mod to Sev Plaque Psoriasis

Completed
NCT01103024Phase 3

Extension Study to Assess Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis

Withdrawn
NCT00770965Phase 2

Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis

Completed
NCT01132612Phase 2

AIN457 Regimen Finding Extension Study in Participants With Moderate to Severe Psoriasis

Completed
NCT00685399Phase 2

Safety and Efficacy of AIN457 in Noninfectious Uveitis

Completed
NCT01350804Phase 3

Efficacy at 24 Weeks and Safety, Tolerability and Long Term Efficacy of Secukinumab (AIN457) in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Anti-Tumor Necrosis Factor α (Anti-TNFα) Agents (CAIN457F2309 and CAIN457F2309E1)

Completed
NCT01433250Phase 2

A Study to Evaluate the Safety, Tolerability and Efficacy of AIN457 in Patients With Relapsing-remitting Multiple Sclerosis

Completed
NCT01093846Phase 3

38 Week Extension Study to CAIN457C2303

Terminated
NCT01090310Phase 3

Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis

Terminated
NCT00809159Phase 2

Double Blind, Placebo Controlled Study to Assess Efficacy of AIN457 in Moderate to Severe Ankylosing Spondylitis

Completed
NCT00809614Phase 2

Efficacy of AIN457 in Adults (18-65 Years) With Psoriatic Arthritis

Completed
NCT01032915Phase 3

Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis

Terminated
NCT01095250Phase 3

Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis

Terminated
NCT00995709Phase 3

Phase III Study in Refractory Behcet's Disease

Completed
NCT00941031Phase 2

AIN457 Regimen Finding Study in Patients With Moderate to Severe Psoriasis

Completed
NCT01874340Phase 2

Efficacy and Safety of AIN457 (Secukinumab) in Patients With Relapsing Multiple Sclerosis

Terminated

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
28