Success Metrics

Clinical Success Rate
90.0%

Based on 9 completed trials

Completion Rate
90%(9/10)
Active Trials
0(0%)
Results Posted
11%(1 trials)
Terminated
1(6%)

Phase Distribution

Ph not_applicable
1
6%
Ph phase_3
7
44%
Ph phase_4
7
44%

Phase Distribution

0

Early Stage

0

Mid Stage

14

Late Stage

Phase Distribution15 total trials
Phase 3Large-scale testing
7(46.7%)
Phase 4Post-market surveillance
7(46.7%)
N/ANon-phased studies
1(6.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

9 of 12 finished

Non-Completion Rate

25.0%

3 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Active(1)
Completed(9)
Terminated(3)
Other(3)

Detailed Status

Completed9
unknown3
Withdrawn2
Terminated1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Phase 37 (46.7%)
Phase 47 (46.7%)
N/A1 (6.7%)

Trials by Status

unknown319%
completed956%
withdrawn213%
terminated16%
not_yet_recruiting16%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT07011693Phase 4

Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression(SMART-I)

Not Yet Recruiting
NCT03852160Phase 3

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Withdrawn
NCT04589143Phase 4

A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine

Completed
NCT05646264Phase 4

A Study on the Efficacy of Agomelatine Combined With Antipsychotics to Treat Negative Symptoms in Schizophrenia

Unknown
NCT05426304Phase 4

Prophylactic Effects of Agomelatine for Poststroke Depression

Unknown
NCT00411099Phase 3

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Completed
NCT00463242Phase 3

A Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD)

Completed
NCT00467402Phase 3

Efficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive Disorder

Completed
NCT00411242Phase 3

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Completed
NCT04181567Phase 4

Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients

Completed
NCT01822418Phase 4

Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH)

Completed
NCT02374567Phase 3

Pharmacovigilance in Gerontopsychiatric Patients

Terminated
NCT01731899

Agomelatine in Depressed Patients With Fibromyalgia

Completed
NCT01488071Phase 3

A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous Medication

Completed
NCT01483053Phase 4

Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD)

Unknown
NCT00451490Not Applicable

The Effect of Agomelatine or Fluoxentine on Heart Rate Variability in Patients With Major Depressive Disorder

Withdrawn

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16