Success Metrics

Clinical Success Rate

81.3%

Based on 52 completed trials

Completion Rate

81%(52/64)

Active Trials

25(23%)

Results Posted

27%(14 trials)

Terminated

12(11%)

Phase Distribution

Ph phase_2

28%

Ph phase_4

25%

Ph phase_3

10%

Ph not_applicable

16%

Ph phase_1

15%

Ph early_phase_1

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution107 total trials

Early Phase 1First-in-human

3(2.8%)

Phase 1Safety & dosage

17(15.9%)

Phase 2Efficacy & side effects

31(29.0%)

Phase 3Large-scale testing

11(10.3%)

Phase 4Post-market surveillance

27(25.2%)

N/ANon-phased studies

18(16.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.2%

52 of 72 finished

Non-Completion Rate

27.8%

20 ended early

Currently Active

trials recruiting

Total Trials

110

all time

Status Distribution

Active(26)

Completed(52)

Terminated(20)

Other(12)

Detailed Status

Completed52

Recruiting18

Terminated12

unknown12

Withdrawn8

Active, not recruiting7

Development Timeline

Analytics

Development Status

Total Trials

110

Active

Success Rate

81.3%

Most Advanced

Phase 4

Trials by Phase

Early Phase 13 (2.8%)

Phase 117 (15.9%)

Phase 231 (29.0%)

Phase 311 (10.3%)

Phase 427 (25.2%)

N/A18 (16.8%)

Trials by Status

active_not_recruiting76%

terminated1211%

unknown1211%

withdrawn87%

enrolling_by_invitation11%

recruiting1816%

completed5247%

Recent Activity

25 active trials

Showing 5 of 110

active_not_recruitingphase_2

Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea

NCT06776432

completedphase_2

Acetazolamide Trial in Normal Pressure Hydrocephalus

NCT04975269

active_not_recruitingphase_1

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

NCT03011671

active_not_recruitingphase_1

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

NCT05470283

completedphase_2

Managing Opioid Related Sleep Apnea With Acetazolamide

NCT06043830

View all 110 trials

Clinical Trials (110)

Showing 20 of 110 trialsScroll for more

NCT06776432Phase 2

Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea

Active Not Recruiting

NCT04975269Phase 2

Acetazolamide Trial in Normal Pressure Hydrocephalus

Completed

NCT03011671Phase 1

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

Active Not Recruiting

NCT05470283Phase 1

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

Active Not Recruiting

NCT06043830Phase 2

Managing Opioid Related Sleep Apnea With Acetazolamide

Completed

NCT06945848Not Applicable

Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide

Recruiting

NCT07372040Phase 2

Add-on Diuretics in Acute Decompensated Heart Failure

Recruiting

NCT06499727Phase 4

HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to Men

Completed

NCT05589792Phase 1

Acetazolamide on REM OSA

Completed

NCT05616260Phase 2

Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health

Completed

NCT06521476Phase 2

Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

Recruiting

NCT00262470Phase 1

Treatment of Orthostatic Intolerance

Active Not Recruiting

NCT07199088Not Applicable

Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

Recruiting

NCT04726982Phase 4

Optimal Dosage of Acetazolamide for OSA Treatment

Completed

NCT02703220Phase 4

Sleep Apnea in Elderly

Recruiting

NCT02390284Phase 3

Stop Retinal Ganglion Cell Dysfunction Study

Terminated

NCT07118462Phase 4

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume