Success Metrics

Clinical Success Rate
94.1%

Based on 16 completed trials

Completion Rate
94%(16/17)
Active Trials
0(0%)
Results Posted
13%(2 trials)
Terminated
1(6%)

Phase Distribution

Ph phase_2
4
22%
Ph phase_1
14
78%

Phase Distribution

14

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
14(77.8%)
Phase 2Efficacy & side effects
4(22.2%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

88.9%

16 of 18 finished

Non-Completion Rate

11.1%

2 ended early

Currently Active

0

trials recruiting

Total Trials

18

all time

Status Distribution
Completed(16)
Terminated(2)

Detailed Status

Completed16
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
0
Success Rate
94.1%
Most Advanced
Phase 2

Trials by Phase

Phase 114 (77.8%)
Phase 24 (22.2%)

Trials by Status

terminated16%
completed1689%
withdrawn16%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT00788684Phase 1

Safety Study of ABT-263 in Combination With Rituximab in Lymphoid Cancers

Completed
NCT00481091Phase 1

A Study of ABT-263 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Completed
NCT00406809Phase 1

A Study of ABT-263 in Subjects With Relapsed or Refractory Lymphoid Malignancies

Completed
NCT02591095Phase 2

A Study of ABT-263 as Single Agent in Women With Platinum Resistant/Refractory Recurrent Ovarian Cancer

Completed
NCT00878449Phase 1

A Study Evaluating the Safety of ABT-263 in Combination With Etoposide/Cisplatin in Subjects With Cancer

Completed
NCT00445198Phase 1

A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies

Completed
NCT00887757Phase 1

Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors

Completed
NCT00982566Phase 1

Assess the Oral Bioavailability of a New ABT-263 Formulation in Subjects With Cancer

Completed
NCT00891605Phase 1

Safety Study of ABT-263 in Combination With Paclitaxel in Subjects With Solid Tumors

Completed
NCT01009073Phase 1

A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects

Completed
NCT01828476Phase 2

Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating Patients With Progressive Metastatic Castrate Refractory Prostate Cancer

Terminated
NCT01087151Phase 2

A Study of ABT-263 in Combination With Dose-Intensive Rituximab, or Dose-Intensive Rituximab Alone, in Previously Untreated Patients With B-Cell, Chronic Lymphocytic Leukemia (CLL)

Completed
NCT00868413Phase 1

Study of ABT-263 When Administered in Combination With Either Fludarabine/Cyclophosphamide/Rituximab or Bendamustine/Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia

Completed
NCT00888108Phase 1

Safety Profile, MTD, and PK Profile Studies of ABT-263 When Administered in Combination With Standard and Weekly Regimens of Docetaxel in Subjects With Cancer

Completed
NCT01021358Phase 1

A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-263 (Navitoclax).

Completed
NCT01053520Phase 1

Assess the Oral Bioavailability of a New ABT-263 Formulation in Healthy Female Subjects

Completed
NCT00743028Phase 1

Assess the Oral Bioavailability of New ABT-263 Formulations

Completed
NCT00918450Phase 2

Study Assessing the Safety and Efficacy of ABT-263 in Subjects With B-cell Chronic Lymphocytic Leukemia (CLL) Who Have Failed at Least One Prior Fludarabine-containing Regimen

Withdrawn

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18