Success Metrics

Clinical Success Rate
70.1%

Based on 54 completed trials

Completion Rate
70%(54/77)
Active Trials
100(52%)
Results Posted
109%(59 trials)
Terminated
23(12%)

Phase Distribution

Ph early_phase_1
5
3%
Ph phase_2
79
41%
Ph phase_3
21
11%
Ph phase_4
5
3%
Ph phase_1
73
38%
Ph not_applicable
1
1%

Phase Distribution

78

Early Stage

79

Mid Stage

26

Late Stage

Phase Distribution184 total trials
Early Phase 1First-in-human
5(2.7%)
Phase 1Safety & dosage
73(39.7%)
Phase 2Efficacy & side effects
79(42.9%)
Phase 3Large-scale testing
21(11.4%)
Phase 4Post-market surveillance
5(2.7%)
N/ANon-phased studies
1(0.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.3%

54 of 84 finished

Non-Completion Rate

35.7%

30 ended early

Currently Active

100

trials recruiting

Total Trials

193

all time

Status Distribution
Active(104)
Completed(54)
Terminated(30)
Other(5)

Detailed Status

Recruiting60
Completed54
Active, not recruiting40
Terminated23
Withdrawn7
unknown5

Development Timeline

Analytics

Development Status

Total Trials
193
Active
100
Success Rate
70.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (2.7%)
Phase 173 (39.7%)
Phase 279 (42.9%)
Phase 321 (11.4%)
Phase 45 (2.7%)
N/A1 (0.5%)

Trials by Status

recruiting6031%
terminated2312%
withdrawn74%
active_not_recruiting4021%
enrolling_by_invitation11%
not_yet_recruiting32%
completed5428%
unknown53%

Recent Activity

Clinical Trials (193)

Showing 20 of 193 trialsScroll for more
NCT02523014Phase 2

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Recruiting
NCT04305834Phase 2

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

Recruiting
NCT06498648Phase 1

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

Recruiting
NCT04923542Phase 1

SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

Recruiting
NCT05867251Phase 1

Study of AVZO-021 in Patients With Advanced Solid Tumors

Recruiting
NCT07492641Phase 3

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

Recruiting
NCT03994796Phase 2

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Active Not Recruiting
NCT03643510Phase 2

Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer

Completed
NCT05708235Phase 2

A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population

Active Not Recruiting
NCT06179303Phase 2

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Recruiting
NCT04964934Phase 3

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Active Not Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT07832227Phase 2

Imlunestrant/Abemaciclib/Selinexor in Ovarian and Endometrial

Not Yet Recruiting
NCT06025747Phase 1

A Phase 1 Study of Neoadjuvant Abemaciclib in Combination With Radiation Therapy for Liposarcomas

Recruiting
NCT04750928Phase 1

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Recruiting
NCT06366347Phase 2

ALPINE: Maintenance Letrozole/Abemaciclib

Recruiting
NCT04921904Phase 1

Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca

Completed
NCT03531645Phase 2

Fulvestrant Plus Abemaciclib in Women With Advanced Low Grade Serous Carcinoma

Active Not Recruiting
NCT06065748Phase 3

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Active Not Recruiting
NCT04633239Phase 1

Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
193