Success Metrics

Clinical Success Rate
90.9%

Based on 10 completed trials

Completion Rate
91%(10/11)
Active Trials
8(32%)
Results Posted
60%(6 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_2
14
56%
Ph phase_4
4
16%
Ph phase_1
3
12%
Ph phase_3
2
8%
Ph not_applicable
1
4%

Phase Distribution

3

Early Stage

14

Mid Stage

6

Late Stage

Phase Distribution24 total trials
Phase 1Safety & dosage
3(12.5%)
Phase 2Efficacy & side effects
14(58.3%)
Phase 3Large-scale testing
2(8.3%)
Phase 4Post-market surveillance
4(16.7%)
N/ANon-phased studies
1(4.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

10 of 12 finished

Non-Completion Rate

16.7%

2 ended early

Currently Active

8

trials recruiting

Total Trials

25

all time

Status Distribution
Active(8)
Completed(10)
Terminated(2)
Other(5)

Detailed Status

Completed10
Recruiting8
unknown5
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
25
Active
8
Success Rate
90.9%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (12.5%)
Phase 214 (58.3%)
Phase 32 (8.3%)
Phase 44 (16.7%)
N/A1 (4.2%)

Trials by Status

unknown520%
recruiting832%
terminated14%
withdrawn14%
completed1040%

Recent Activity

Clinical Trials (25)

Showing 20 of 25 trialsScroll for more
NCT04043494Phase 3

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

Recruiting
NCT06533748Phase 2

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

Recruiting
NCT06387121Phase 2

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL

Recruiting
NCT05660473Phase 2

Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Recruiting
NCT02303821Phase 1

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Completed
NCT03384654Phase 2

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Completed
NCT03643276Phase 3

Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017

Recruiting
NCT06279767Phase 1

Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma

Recruiting
NCT00199056Phase 4

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)

Completed
NCT00199069Phase 4

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)

Completed
NCT03286634Phase 2

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

Recruiting
NCT05506332Phase 1

Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT01324336

Comparative Pharmacokinetics of a Compounded 6-mercaptopurine Liquid Formulation Preparation and Tablets

Completed
NCT04228393Phase 2

The Individualized Treatment of 6-mercaptopurine in Children With Acute Lymphoblastic Leukemia in China

Unknown
NCT01432145Phase 2

A Clinical Trial in Patients With Breast Cancer Susceptibility Gene (BRCA) Defective Tumours

Completed
NCT02518750Phase 2

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma

Terminated
NCT03564704Phase 2

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL

Unknown
NCT03553238Phase 2

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL

Unknown
NCT00602134Not Applicable

Bioequivalence Study of 6-Mercaptopurine Under Fasting Conditions

Completed
NCT00514982Phase 2

Medical Treatment of Colitis in Patients With Hermansky-Pudlak Syndrome

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
25