Success Metrics

Clinical Success Rate
80.3%

Based on 175 completed trials

Completion Rate
80%(175/218)
Active Trials
63(18%)
Results Posted
55%(96 trials)
Terminated
43(12%)

Phase Distribution

Ph not_applicable
11
3%
Ph phase_2
167
47%
Ph phase_3
90
25%
Ph early_phase_1
4
1%
Ph phase_1
65
18%
Ph phase_4
13
4%

Phase Distribution

69

Early Stage

167

Mid Stage

103

Late Stage

Phase Distribution350 total trials
Early Phase 1First-in-human
4(1.1%)
Phase 1Safety & dosage
65(18.6%)
Phase 2Efficacy & side effects
167(47.7%)
Phase 3Large-scale testing
90(25.7%)
Phase 4Post-market surveillance
13(3.7%)
N/ANon-phased studies
11(3.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.5%

175 of 238 finished

Non-Completion Rate

26.5%

63 ended early

Currently Active

63

trials recruiting

Total Trials

353

all time

Status Distribution
Active(76)
Completed(175)
Terminated(63)
Other(39)

Detailed Status

Completed175
Recruiting45
Terminated43
unknown39
Withdrawn20
Active, not recruiting18

Development Timeline

Analytics

Development Status

Total Trials
353
Active
63
Success Rate
80.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (1.1%)
Phase 165 (18.6%)
Phase 2167 (47.7%)
Phase 390 (25.7%)
Phase 413 (3.7%)
N/A11 (3.1%)

Trials by Status

enrolling_by_invitation21%
not_yet_recruiting113%
unknown3911%
active_not_recruiting185%
completed17550%
recruiting4513%
terminated4312%
withdrawn206%

Recent Activity

Clinical Trials (353)

Showing 20 of 353 trialsScroll for more
NCT06750094Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Recruiting
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT06219941Phase 2

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Recruiting
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting
NCT07730021Phase 1

A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors

Not Yet Recruiting
NCT05253846Phase 2

Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29

Active Not Recruiting
NCT06997497Phase 3

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Recruiting
NCT07441369Phase 2

Abemaciclib Combined With FOLFOX/FOLFIRI Regimen in Patients With Advanced Colorectal Liver Metastases Cancer

Enrolling By Invitation
NCT06607185Phase 1

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Active Not Recruiting
NCT05152147Phase 3

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Active Not Recruiting
NCT06948448Phase 2

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Recruiting
NCT07554456Phase 2

A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)

Recruiting
NCT05062317Phase 2

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

Recruiting
NCT07621718Phase 3

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Recruiting
NCT04375605Phase 3

Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ

Completed
NCT06057038Phase 1

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

Active Not Recruiting
NCT06123338Phase 2

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Recruiting
NCT06461442Phase 4

Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis

Enrolling By Invitation
NCT07431281Phase 3

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
353