Success Metrics

Clinical Success Rate
80.3%

Based on 175 completed trials

Completion Rate
80%(175/218)
Active Trials
66(18%)
Results Posted
55%(97 trials)
Terminated
43(12%)

Phase Distribution

Ph phase_4
16
4%
Ph phase_3
90
25%
Ph not_applicable
12
3%
Ph phase_1
65
18%
Ph phase_2
169
47%
Ph early_phase_1
4
1%

Phase Distribution

69

Early Stage

169

Mid Stage

106

Late Stage

Phase Distribution356 total trials
Early Phase 1First-in-human
4(1.1%)
Phase 1Safety & dosage
65(18.3%)
Phase 2Efficacy & side effects
169(47.5%)
Phase 3Large-scale testing
90(25.3%)
Phase 4Post-market surveillance
16(4.5%)
N/ANon-phased studies
12(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.5%

175 of 238 finished

Non-Completion Rate

26.5%

63 ended early

Currently Active

66

trials recruiting

Total Trials

359

all time

Status Distribution
Active(82)
Completed(175)
Terminated(63)
Other(39)

Detailed Status

Completed175
Recruiting48
Terminated43
unknown39
Withdrawn20
Active, not recruiting18

Development Timeline

Analytics

Development Status

Total Trials
359
Active
66
Success Rate
80.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (1.1%)
Phase 165 (18.3%)
Phase 2169 (47.5%)
Phase 390 (25.3%)
Phase 416 (4.5%)
N/A12 (3.4%)

Trials by Status

not_yet_recruiting144%
recruiting4813%
withdrawn206%
enrolling_by_invitation21%
completed17549%
terminated4312%
unknown3911%
active_not_recruiting185%

Recent Activity

Clinical Trials (359)

Showing 20 of 359 trialsScroll for more
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting
NCT05203172Phase 4

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Recruiting
NCT06997497Phase 3

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Recruiting
NCT06219941Phase 2

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Recruiting
NCT03358472Phase 3

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

Completed
NCT07621718Phase 3

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Recruiting
NCT05007106Phase 2

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

Completed
NCT05610163Phase 2

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation and Continuing Response

Active Not Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT06750094Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Recruiting
NCT07837908Not Applicable

Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma

Not Yet Recruiting
NCT06123338Phase 2

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Recruiting
NCT05152147Phase 3

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Active Not Recruiting
NCT05489211Phase 2

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Recruiting
NCT07829757Phase 4

A Study of Zolbetuximab Given With mFOLFOX6 or CAPOX Chemotherapy in Indian Adults With Gastric Cancer

Not Yet Recruiting
NCT07096362Phase 2

Utility of ctDNA in Early Switch of First-line Chemotherapy in Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT07730021Phase 1

A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors

Recruiting
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT07814417Phase 2

A Study of Olomorasib (LY3537982) in Participants With Advanced Colorectal Cancer and a KRAS G12C Mutation

Not Yet Recruiting
NCT06764875Phase 3

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
359