5-azacytidine
5-azacytidine is a pharmaceutical drug with 18 clinical trials. Currently 2 active trials ongoing. Historical success rate of 75.0%.
Success Metrics
Based on 9 completed trials
Phase Distribution
Phase Distribution
10
Early Stage
8
Mid Stage
0
Late Stage
Highest Phase Reached
Phase 2Trial Status & Enrollment
60.0%
9 of 15 finished
40.0%
6 ended early
2
trials recruiting
18
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
5-Azacytidine With Steroids for Gastrointestinal GVHD (5-AZA FOR GVHD)
5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
Phase I/II - Brentuximab/5-Azacytidine in Acute Myeloid Leukemia (AML)
Clinical Trials (18)
5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
5-Azacytidine With Steroids for Gastrointestinal GVHD (5-AZA FOR GVHD)
5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
Phase I/II - Brentuximab/5-Azacytidine in Acute Myeloid Leukemia (AML)
Nivolumab in Combination With 5-azacytidine in Childhood Relapsed/Refractory AML
Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR
A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).
Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Ependymoma
PKC412 and 5-Azacytidine
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS
Dose-Escalation Study of Ponatinib, a FLT3 Inhibitor, With and Without Combination of 5-Azacytidine, in Patients With FLT3-Mutated Acute Myeloid Leukemia (AML)
Azacitidine and Lintuzumab in Treating Patients With Previously Untreated Myelodysplastic Syndromes
5-Azacytidine With Lenalidomide in Patients With High Risk Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
5-Azacytidine Prior to Allogeneic Stem Cell Transplant in High Risk Myelodysplastic Syndrome
5-Azacytidine (Azacytidine; Vidaza) in Chronic Lymphocytic Leukemia
Azacytidine With Valproic Acid Versus Ara-C in Acute Myeloid Leukemia (AML)/ Myelodysplastic Syndrome (MDS) Patients
5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia
All 18 trials loaded
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 18