Success Metrics

Clinical Success Rate
75.0%

Based on 6 completed trials

Completion Rate
75%(6/8)
Active Trials
18(60%)
Results Posted
83%(5 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_1
12
40%
Ph phase_3
4
13%
Ph phase_2
11
37%

Phase Distribution

12

Early Stage

11

Mid Stage

4

Late Stage

Phase Distribution27 total trials
Phase 1Safety & dosage
12(44.4%)
Phase 2Efficacy & side effects
11(40.7%)
Phase 3Large-scale testing
4(14.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

60.0%

6 of 10 finished

Non-Completion Rate

40.0%

4 ended early

Currently Active

18

trials recruiting

Total Trials

30

all time

Status Distribution
Active(18)
Completed(6)
Terminated(4)
Other(2)

Detailed Status

Active, not recruiting10
Recruiting8
Completed6
Withdrawn2
Terminated2
unknown2

Development Timeline

Analytics

Development Status

Total Trials
30
Active
18
Success Rate
75.0%
Most Advanced
Phase 3

Trials by Phase

Phase 112 (44.4%)
Phase 211 (40.7%)
Phase 34 (14.8%)

Trials by Status

withdrawn27%
completed620%
terminated27%
recruiting827%
unknown27%
active_not_recruiting1033%

Recent Activity

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT04689828Phase 3

177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer

Active Not Recruiting
NCT05079698Phase 1

A Study of Stereotactic Body Radiotherapy and 177Lu-PSMA-617 for the Treatment of Prostate Cancer

Active Not Recruiting
NCT06461689

Comparison of Changes in Tumor Burden in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in Metastatic Castration-resistant Prostate Cancer

Completed
NCT04886986Phase 1

Phase I Study of 225Ac-J591 Plus 177Lu-PSMA Small Molecule for Progressive Metastatic Castration Resistant Prostate Cancer

Recruiting
NCT04720157Phase 3

An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Active Not Recruiting
NCT06783348Phase 2

Radiopharmaceutical Treatment of Advanced Kidney Cancer

Recruiting
NCT07223034Phase 1

A Study of 177Lu-PSMA-617 in People With Gliomas

Recruiting
NCT07145177Phase 1

177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

Recruiting
NCT05114746Phase 2

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan

Completed
NCT07025512Phase 2

177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia

Withdrawn
NCT05766371Phase 2

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

Recruiting
NCT06303713Phase 1

LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer

Active Not Recruiting
NCT06389097

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

Recruiting
NCT04663997Phase 2

177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer

Active Not Recruiting
NCT04443062Phase 2

Lutetium-177-PSMA-617 in Oligo-metastatic Hormone Sensitive Prostate Cancer

Completed
NCT06964958Phase 2

177LuPSMA in Renal Cell Carcinoma

Active Not Recruiting
NCT05162573Phase 1

EBRT + Lu-PSMA for N1M0 Prostate Cancer

Completed
NCT06320067Phase 3

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer

Recruiting
NCT03042468Phase 1

Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC

Active Not Recruiting
NCT06943495Phase 1

Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
30