Key Insights

Highlights

Success Rate

76% trial completion

Published Results

39 trials with published results (41%)

Research Maturity

65 completed trials (69% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

21.3%

20 terminated out of 94 trials

Success Rate

76.5%

-10.0% vs benchmark

Late-Stage Pipeline

4%

4 trials in Phase 3/4

Results Transparency

60%

39 of 65 completed with results

Key Signals

39 with results76% success20 terminated

Data Visualizations

Phase Distribution

92Total
Not Applicable (11)
Early P 1 (2)
P 1 (48)
P 2 (27)
P 3 (1)
P 4 (3)

Trial Status

Completed65
Terminated20
Recruiting3
Withdrawn3
Unknown2
Active Not Recruiting1

Trial Success Rate

76.5%

Benchmark: 86.5%

Based on 65 completed trials

Clinical Trials (94)

Showing 20 of 20 trials
NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT05294731Phase 1Recruiting

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT02213913Phase 1Completed

Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas

NCT02844309Phase 4CompletedPrimary

The Efficacy of TCD Following by TP Maintenance Therapy in Newly Diagnosed WM

NCT02844361Phase 4CompletedPrimary

Comparison of ASCT and Conventional Chemotherapy in High Risk Waldenström Macroglobulinemia

NCT02844322Phase 4CompletedPrimary

The Comparison of RCD Versus BCD in Newly Diagnosed Waldenström Macroglobulinemia

NCT04463953Phase 2CompletedPrimary

Zanubrutinib, Ixazomib and Dexamethasone in Patients With Treatment Naive Waldenstrom's Macroglobulinemia

NCT02362035Phase 1Completed

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

NCT06986174Phase 2RecruitingPrimary

A Phase 2 Study to Evaluate the Safety and Efficacy of Pacritinib in Relapsed or Refractory Waldenström Macroglobulinemia

NCT01815749Phase 1Active Not Recruiting

Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma

NCT04052854UnknownPrimary

A Single-Arm, Expanded Access Study of Zanubrutinib in Participants With B-cell Malignancies

NCT01588015Phase 1Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT06224309Unknown

Preliminary Assessment of [18F]BL40 in PET/CT Scans

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT01044745Phase 2Terminated

Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

NCT03187262Phase 2CompletedPrimary

A Study of Daratumumab in Patients With Relapsed or Refractory Waldenström Macroglobulinemia

NCT02049541Phase 1Completed

Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma

NCT01805037Phase 1Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

NCT02640287Not ApplicableCompletedPrimary

Expression of Ku70/XRCC6 in Waldenström's Macroglobulinemia

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