Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

11.9%

5 terminated out of 42 trials

Success Rate

85.3%

-1.2% vs benchmark

Late-Stage Pipeline

29%

12 trials in Phase 3/4

Results Transparency

0%

0 of 29 completed with results

Key Signals

85% success

Data Visualizations

Phase Distribution

32Total
Not Applicable (10)
P 1 (4)
P 2 (6)
P 3 (8)
P 4 (4)

Trial Status

Completed29
Terminated5
Unknown4
Active Not Recruiting2
Recruiting2

Trial Success Rate

85.3%

Benchmark: 86.5%

Based on 29 completed trials

Clinical Trials (42)

Showing 20 of 20 trials
NCT06983665Not ApplicableActive Not Recruiting

Human Bioequivalence Study of Liposomal Amphotericin B for Injection

NCT07487350Recruiting

Recurrent Visceral Leishmaniasis in HIV Co-Infection

NCT06977490Not ApplicableCompleted

Human Bioequivalence Study of Amphotericin B Liposome for Injection

NCT04342715Active Not RecruitingPrimary

A Study to Assess Immune Response Status in Patients Before and After Treatment for Visceral Leishmaniasis

NCT06118749TerminatedPrimary

Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation Study

NCT05602610RecruitingPrimary

Clinical Prognostic Score to Predict Relapse in VL

NCT03129646Phase 3CompletedPrimary

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

NCT04003532CompletedPrimary

LAMP Assay for the Diagnosis of Visceral Leishmaniasis

NCT05386875UnknownPrimary

Evaluation to Assess the Usability of rK28 for the Diagnosis of Visceral Leishmaniasis in Kenya

NCT03929016Phase 1CompletedPrimary

Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects

NCT05426577UnknownPrimary

Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of Cure

NCT03269006Not ApplicableCompletedPrimary

Improved Case Detection and Vector Control for Visceral Leishmaniasis

NCT03636659Phase 1CompletedPrimary

Steady State Global Bioequivalence Study of Amphotericin B Liposome for Injection 50 mg/ Vial in Fed Condition

NCT02011958Phase 3CompletedPrimary

Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.

NCT02839603TerminatedPrimary

Asymptomatic Leishmania Infection in HIV Patients

NCT01240473Not ApplicableCompletedPrimary

A Pilot Study for Capacity Building for a Multi-centre, Randomized Trial for Treatment of Kala Azar in Bangladesh

NCT01032187Phase 4CompletedPrimary

Amphotericin B to Treat Visceral Leishmaniasis in Brazilian Children

NCT01310738Phase 4TerminatedPrimary

Efficacy and Safety Study of Drugs for Treatment of Visceral Leishmaniasis in Brazil

NCT00342823CompletedPrimary

Immunogenetics of Visceral Leishmaniasis

NCT01766830Not ApplicableCompletedPrimary

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)

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Research Network

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