Key Insights

Highlights

Success Rate

84% trial completion

Published Results

44 trials with published results (44%)

Research Maturity

77 completed trials (78% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.2%

15 terminated out of 99 trials

Success Rate

83.7%

-2.8% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

57%

44 of 77 completed with results

Key Signals

44 with results84% success15 terminated

Data Visualizations

Phase Distribution

98Total
Not Applicable (8)
Early P 1 (1)
P 1 (44)
P 2 (37)
P 3 (8)

Trial Status

Completed77
Terminated15
Active Not Recruiting2
Unknown2
Recruiting2
Withdrawn1

Trial Success Rate

83.7%

Benchmark: 86.5%

Based on 77 completed trials

Clinical Trials (99)

Showing 20 of 20 trials
NCT03009240Phase 1Completed

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

NCT00801489Phase 2Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT02835222Phase 2Active Not RecruitingPrimary

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

NCT02115295Phase 2Recruiting

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

NCT02159495Phase 1Active Not Recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

NCT01822015Early Phase 1Completed

Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02085408Phase 3Completed

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02096055Phase 2CompletedPrimary

Guadecitabine With or Without Idarubicin or Cladribine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

NCT00085124Phase 3Completed

Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia

NCT01588015Phase 1Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT02583893Phase 2Completed

Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia

NCT02122081Phase 1Completed

Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

NCT01044745Phase 2Terminated

Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

NCT01806571Phase 2CompletedPrimary

Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02581917Completed

Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia

NCT01555268Phase 1Completed

Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia

NCT01093573Phase 1CompletedPrimary

Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

NCT01876953Phase 1Terminated

Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid Leukemia

NCT00352365Phase 2Completed

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

NCT02144675Phase 2Completed

Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia

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