Key Insights

Highlights

Success Rate

78% trial completion

Published Results

12 trials with published results (48%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

16.0%

4 terminated out of 25 trials

Success Rate

77.8%

-8.7% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

86%

12 of 14 completed with results

Key Signals

12 with results78% success

Data Visualizations

Phase Distribution

25Total
P 1 (23)
P 2 (2)

Trial Status

Completed14
Active Not Recruiting5
Terminated4
Withdrawn2

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT01012817Phase 1Active Not Recruiting

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

NCT03218826Phase 1Completed

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

NCT01787500Phase 1Completed

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

NCT02535312Phase 1Active Not Recruiting

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

NCT04957615Phase 2Active Not Recruiting

Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expression

NCT02721732Phase 2Active Not Recruiting

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

NCT02432963Phase 1Active Not Recruiting

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

NCT02408861Phase 1Terminated

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT02159989Phase 1Completed

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT00576654Phase 1Completed

Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery

NCT02070549Phase 1Completed

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

NCT02503709Phase 1Completed

Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT01638533Phase 1Completed

Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

NCT02143401Phase 1Completed

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

NCT02097225Phase 1Terminated

Onalespib, Dabrafenib, and Trametinib in Treating Patients With BRAF-Mutant Melanoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT03087591Phase 1Completed

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

NCT03061188Phase 1Completed

Phase I/Ib Study of Nivolumab & Veliparib in Patients With Advanced Solid Tumors & Lymphoma

NCT04250597Phase 1Terminated

Study of GNX102 in Patients With Advanced Solid Tumors

NCT01738139Phase 1Completed

Ipilimumab and Imatinib Mesylate in Advanced Cancer

NCT03229278Phase 1Completed

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

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