Key Insights

Highlights

Success Rate

70% trial completion

Published Results

24 trials with published results (35%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

13.2%

9 terminated out of 68 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

114%

24 of 21 completed with results

Key Signals

24 with results70% success

Data Visualizations

Phase Distribution

66Total
P 1 (31)
P 2 (30)
P 3 (4)
P 4 (1)

Trial Status

Completed21
Active Not Recruiting19
Recruiting10
Terminated9
Withdrawn5
Unknown3

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (68)

Showing 20 of 20 trials
NCT05136196Phase 2Recruiting

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

NCT04462406Phase 2Active Not Recruiting

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

NCT02196181Phase 2Active Not Recruiting

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

NCT05896839Phase 1Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

NCT03816332Phase 1Active Not Recruiting

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

NCT06151847Phase 2Completed

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

NCT01134614Phase 2Active Not Recruiting

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT05764395Phase 2Active Not Recruiting

Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors

NCT06624644Phase 2Recruiting

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

NCT05398640UnknownPrimary

Expanded Access Program of AMTAGVI That is Out of Specification for Commercial Release

NCT07288203Phase 2Active Not Recruiting

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma

NCT01989585Phase 1Active Not Recruiting

Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT04527549Phase 2Terminated

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

NCT06466434Phase 2RecruitingPrimary

Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma

NCT04007744Phase 1Active Not Recruiting

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT07459543Phase 4Not Yet Recruiting

A Study To Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Untreated, Unresectable or Metastatic Melanoma Participants In India

NCT04940299Phase 2Active Not Recruiting

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

NCT03501368Phase 1Completed

Study of Trametinib + Ceritinib in Patients With Unresectable Melanoma

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