Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

4.1%

3 terminated out of 74 trials

Success Rate

85.0%

-1.5% vs benchmark

Late-Stage Pipeline

15%

11 trials in Phase 3/4

Results Transparency

53%

9 of 17 completed with results

Key Signals

9 with results85% success

Data Visualizations

Phase Distribution

58Total
Not Applicable (10)
P 1 (15)
P 2 (22)
P 3 (8)
P 4 (3)

Trial Status

Recruiting18
Completed17
Active Not Recruiting15
Not Yet Recruiting9
Unknown8
Withdrawn4

Trial Success Rate

85.0%

Benchmark: 86.5%

Based on 17 completed trials

Clinical Trials (74)

Showing 20 of 20 trials
NCT04175912Phase 2Active Not Recruiting

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

NCT03695250Phase 1Terminated

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

NCT07729618Not ApplicableNot Yet RecruitingPrimary

AI-Guided First-Line Immunotherapy Selection in Unresectable Hepatocellular Carcinoma

NCT07227012Phase 1Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

NCT03942328Phase 1Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

NCT06117891Active Not RecruitingPrimary

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

NCT03186898Phase 3Active Not Recruiting

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

NCT07679061RecruitingPrimary

First-Line Nivolumab Plus Ipilimumab in Unresectable Hepatocellular Carcinoma (J-PROMISE)

NCT07110233Not ApplicableNot Yet Recruiting

Yttrium-90 Radiation Segmentectomy for Hepatocellular Carcinoma

NCT01015833Phase 3Completed

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT04829383Phase 2CompletedPrimary

A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma

NCT06902246Phase 2WithdrawnPrimary

Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma

NCT06900543Phase 3Active Not RecruitingPrimary

Chinese HCC Efficacy Evaluation, Response and Safety Study of TareSphere

NCT05667064CompletedPrimary

Imfinzi/Imjudo uHCC Japan PMS _ Japan Post-Marketing Surveillance (PMS) Study

NCT05507632Phase 2Active Not RecruitingPrimary

Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma

NCT03896646Not ApplicableActive Not Recruiting

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

NCT04770896Phase 3Active Not RecruitingPrimary

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

NCT03107416Phase 1Active Not RecruitingPrimary

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

NCT05103904Phase 2Terminated

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

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