Key Insights

Highlights

Success Rate

84% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

4.2%

3 terminated out of 72 trials

Success Rate

84.2%

-2.3% vs benchmark

Late-Stage Pipeline

15%

11 trials in Phase 3/4

Results Transparency

50%

8 of 16 completed with results

Key Signals

8 with results84% success

Data Visualizations

Phase Distribution

57Total
Not Applicable (9)
P 1 (15)
P 2 (22)
P 3 (8)
P 4 (3)

Trial Status

Recruiting20
Completed16
Active Not Recruiting13
Not Yet Recruiting9
Unknown8
Terminated3

Trial Success Rate

84.2%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT03186898Phase 3Active Not Recruiting

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

NCT03107416Phase 1Active Not RecruitingPrimary

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

NCT06902246Phase 2RecruitingPrimary

Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma

NCT05103904Phase 2Terminated

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

NCT04605731Phase 1Active Not Recruiting

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

NCT03942328Phase 1Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

NCT07227012Phase 1Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

NCT06117891RecruitingPrimary

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

NCT06485466Phase 3RecruitingPrimary

TACE Plus Camrelizumab and Apatinib for Unresectable Hepatocellular Carcinoma

NCT07482059Phase 1RecruitingPrimary

A Multicenter Clinical Study of Combined Therapy for Unresectable Hepatocellular Carcinoma

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT05667064CompletedPrimary

Imfinzi/Imjudo uHCC Japan PMS _ Japan Post-Marketing Surveillance (PMS) Study

NCT05096715Phase 1RecruitingPrimary

Atezolizumab+Bevacizumab+SBRT in Unresectable HCC

NCT04770896Phase 3Active Not RecruitingPrimary

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

NCT05176223Phase 2Completed

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

NCT04736121Not ApplicableActive Not RecruitingPrimary

Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients

NCT06310590Phase 1CompletedPrimary

Safety and Efficacy of TareSphere in Patients With Unresectable Hepatocellular Carcinoma

NCT07110233Not ApplicableNot Yet Recruiting

Yttrium-90 Radiation Segmentectomy for Hepatocellular Carcinoma

NCT07351513Phase 2Not Yet RecruitingPrimary

A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma

NCT07305428Not ApplicableRecruiting

Downstaging Unresectable Hepatocellular Carcinoma to Resectable Disease With Combined Immunotherapy and Stereotactic Beamed Radiotherapy: a Pilot Study

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