Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

4.0%

1 terminated out of 25 trials

Success Rate

87.5%

+1.0% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

43%

3 of 7 completed with results

Key Signals

3 with results88% success

Data Visualizations

Phase Distribution

24Total
Not Applicable (4)
P 1 (6)
P 2 (14)

Trial Status

Completed7
Recruiting6
Active Not Recruiting4
Unknown3
Withdrawn2
Not Yet Recruiting2

Trial Success Rate

87.5%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT04332874Phase 2Recruiting

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

NCT02923778Phase 2Active Not Recruiting

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

NCT04420975Phase 1Active Not Recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

NCT04008238Not ApplicableCompleted

Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients

NCT03307616Phase 2Active Not Recruiting

Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery

NCT04055220Not ApplicableRecruiting

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

NCT05182164Phase 2Recruiting

Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas

NCT03425279Phase 1CompletedPrimary

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

NCT04242238Phase 1Completed

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

NCT03899805Phase 2Completed

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

NCT04123535Not ApplicableRecruitingPrimary

Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma

NCT06277154Phase 2Recruiting

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

NCT06526897Not ApplicableNot Yet Recruiting

Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma

NCT03752398Phase 1Completed

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)

NCT04480502Phase 2Active Not RecruitingPrimary

ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma

NCT02584309Phase 2Completed

Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

NCT05961761Phase 2Recruiting

Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients

NCT05515068Not Yet Recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas

NCT05116800Phase 2Withdrawn

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

NCT04099277Phase 1Terminated

A Study of LY3435151 in Participants With Solid Tumors

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Research Network

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