Key Insights

Highlights

Success Rate

69% trial completion

Published Results

27 trials with published results (33%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

16.9%

14 terminated out of 83 trials

Success Rate

68.9%

-17.6% vs benchmark

Late-Stage Pipeline

4%

3 trials in Phase 3/4

Results Transparency

87%

27 of 31 completed with results

Key Signals

27 with results69% success14 terminated

Data Visualizations

Phase Distribution

79Total
Not Applicable (11)
Early P 1 (1)
P 1 (35)
P 2 (29)
P 3 (3)

Trial Status

Completed31
Active Not Recruiting21
Terminated14
Recruiting8
Withdrawn5
Suspended3

Trial Success Rate

68.9%

Benchmark: 86.5%

Based on 31 completed trials

Clinical Trials (83)

Showing 20 of 20 trials
NCT02208375Phase 1Active Not Recruiting

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

NCT04491942Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

NCT02954874Phase 3Active Not Recruiting

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

NCT02445391Phase 3Active Not Recruiting

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

NCT01116648Phase 1Active Not Recruiting

Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer

NCT02883062Phase 2Active Not Recruiting

Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer

NCT01251874Phase 1Active Not Recruiting

Veliparib and Carboplatin in Treating Patients With HER2-Negative Metastatic Breast Cancer

NCT04314401Active Not Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

NCT04052555Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

NCT05111561Phase 1Suspended

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

NCT02689427Phase 2Completed

Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer

NCT02488967Phase 3Active Not Recruiting

Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

NCT05455658Phase 2Active Not Recruiting

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

NCT02498613Phase 2Active Not Recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

NCT03218826Phase 1Completed

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

NCT02957968Phase 2Active Not Recruiting

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

NCT02744053Early Phase 1Active Not Recruiting

DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer

NCT03971409Phase 2Active Not Recruiting

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

NCT02876107Phase 2Active Not Recruiting

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

NCT06422455Not ApplicableRecruiting

Access to Genetic Testing in Underserved Patients With Cancer

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