Key Insights

Highlights

Success Rate

70% trial completion

Published Results

31 trials with published results (25%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

12.3%

15 terminated out of 122 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

14%

17 trials in Phase 3/4

Results Transparency

89%

31 of 35 completed with results

Key Signals

31 with results70% success15 terminated

Data Visualizations

Phase Distribution

116Total
Not Applicable (7)
Early P 1 (1)
P 1 (36)
P 2 (55)
P 3 (15)
P 4 (2)

Trial Status

Completed35
Recruiting30
Unknown19
Terminated15
Active Not Recruiting11
Withdrawn5

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 35 completed trials

Clinical Trials (122)

Showing 20 of 20 trials
NCT07178730Phase 3Not Yet Recruiting

NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer

NCT06393374Phase 3RecruitingPrimary

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT05783622Phase 1Active Not Recruiting

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

NCT05492682Phase 1Recruiting

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

NCT06382142Phase 3Active Not RecruitingPrimary

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer(PANKU-Breast02)

NCT07525869Not ApplicableRecruitingPrimary

An Open-label Prospective Study to Evaluate the Efficacy and Safety of Pegfilgrastim in Triple-Negative Breast Cancer Patients Receiving AC Regimen Following Paclitaxel and Carboplatin as Neoadjuvant Therapy

NCT05749588Phase 2RecruitingPrimary

FUSCC Refractory TNBC Platform Study (FUTURE2.0)

NCT04085276Phase 3CompletedPrimary

Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment

NCT07045311Phase 2RecruitingPrimary

JS207 Combination Therapy in Triple-negative Breast Cancer

NCT06358573Phase 2RecruitingPrimary

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

NCT01525966Phase 2Active Not Recruiting

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer

NCT05806060Phase 3RecruitingPrimary

Precise Treatment for BLIS Subtype of TNBC in the First-line Treatment of Locally Advanced or Metastatic Breast Cancer

NCT07458204Phase 2Not Yet RecruitingPrimary

Peritumoral and Periganglionic Infiltration of Levobupivacaine Prior to Conservative Surgery for Triple-negative Breast Cancer

NCT03017573Not ApplicableRecruiting

Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)

NCT04770272Phase 2TerminatedPrimary

Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy

NCT06418126Not ApplicableActive Not RecruitingPrimary

Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer

NCT04148911Phase 3CompletedPrimary

A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

NCT06817525Phase 2RecruitingPrimary

Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC

NCT05076682Phase 2RecruitingPrimary

Reverse Triple Negative Immune Resistant Breast Cancer

NCT06078384Phase 2RecruitingPrimary

Pembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage TNBC

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