Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

13.6%

3 terminated out of 22 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

27%

6 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed with results

Key Signals

3 with results67% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (9)
Early P 1 (1)
P 2 (2)
P 3 (3)
P 4 (3)

Trial Status

Recruiting7
Completed6
Unknown4
Terminated3
Suspended1
Active Not Recruiting1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT05259306Not ApplicableSuspendedPrimary

Low-Intensity Focused Ultrasound Neuromodulation of the Mediodorsal Thalamus for Treatment-Resistant Schizophrenia

NCT02361554Not ApplicableRecruitingPrimary

Deep Brain Stimulation in Treatment Resistant Schizophrenia

NCT05741502Phase 4TerminatedPrimary

An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine

NCT07184619Phase 3RecruitingPrimary

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

NCT06749444Not ApplicableRecruiting

Cognitive Behavioral Therapy for Sleep and Circadian Disturbances (CBT-I) in Treatment-Resistant Schizophrenia

NCT05299749Not ApplicableRecruiting

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

NCT05337904Not ApplicableActive Not RecruitingPrimary

Deep Brain Stimulation Recovery in Treatment-Resistant Schizophrenia

NCT03983018Phase 2Completed

Rituximab for Schizophrenia Spectrum Disorder (RITS-PS-2019)

NCT03076346Completed

Neural Biomarkers of Clozapine Response

NCT06270108Early Phase 1RecruitingPrimary

The Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant Schizophrenia

NCT04054778Not ApplicableRecruiting

Comparaison of Avatar Therapy to Cognitive Behavioral Therapy in Schizophrenia With Treatment Refractory Hallucinations

NCT06128408UnknownPrimary

The Characteristics of Treatment Resistant Schizophrenia From the Illness Onset

NCT06060886Phase 4Unknown

Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis

NCT01431326Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT05694000Not ApplicableUnknownPrimary

Hippocampus DBS in Treatment-resistant Schizophrenia

NCT03868839Phase 2Terminated

Telmisartan Pilot Study on Treatment Resistant Schizophrenia

NCT05074732Recruiting

Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.

NCT04528095Phase 3UnknownPrimary

SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia

NCT03585127Not ApplicableCompleted

Avatar Therapy in Comparison to Cognitive Behavioral Therapy for Treatment-resistant Schizophrenia

NCT03230864Phase 3TerminatedPrimary

Efficacy of Lu AF35700 in Patients With Early-in-disease or Late-in-disease Treatment-resistant Schizophrenia

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Research Network

Activity Timeline