Transthyretin Amyloidosis
39
7
9
19
Key Insights
Highlights
Success Rate
95% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
2.6%
1 terminated out of 39 trials
95.0%
+8.5% vs benchmark
13%
5 trials in Phase 3/4
26%
5 of 19 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 19 completed trials
Clinical Trials (39)
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
The Eplontersen Pregnancy and Lactation Outcomes Study
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey
Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy
HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran
Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical Records
Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery
Phenotyping and Characterization of wtATTR-CM (TRACE 1)
Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTR
TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects
Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
PL_GNT01_ISR_Grant 53234273
Transthyretin Amyloidosis Outcome Survey (THAOS)
Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis
Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy