Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 15/100

Termination Rate

0.0%

0 terminated out of 12 trials

Success Rate

100.0%

+13.4% vs benchmark

Late-Stage Pipeline

25%

3 trials in Phase 3/4

Results Transparency

100%

1 of 1 completed with results

Key Signals

1 with results100% success

Data Visualizations

Phase Distribution

7Total
Not Applicable (2)
P 1 (1)
P 2 (1)
P 3 (3)

Trial Status

Recruiting5
Active Not Recruiting3
Enrolling By Invitation2
Not Yet Recruiting1
Completed1

Trial Success Rate

100.0%

Benchmark: 86.6%

Based on 1 completed trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT07506863Phase 3Recruiting

A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

NCT04770779Phase 3Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

NCT07680803Phase 2RecruitingPrimary

Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia

NCT07055503Enrolling By InvitationPrimary

Use of the Hemanext One® Hypoxic Red Blood Cell Storage System for Transfusion in Thalassemia Patients

NCT05860595Not ApplicableActive Not RecruitingPrimary

Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.

NCT06219239Not ApplicableRecruitingPrimary

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

NCT02633943Active Not RecruitingPrimary

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

NCT06363760Enrolling By Invitation

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

NCT06280378Phase 1RecruitingPrimary

Β-Thalassemia Treatment with KL003 Cell Injection

NCT06512298Not Yet Recruiting

Plasticizer Exposure and Its Consequences on Health

NCT06146478Phase 3CompletedPrimary

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

NCT05991336RecruitingPrimary

Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy

Showing all 12 trials

Research Network

Activity Timeline