Key Insights

Highlights

Success Rate

83% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

15.4%

2 terminated out of 13 trials

Success Rate

83.3%

-3.2% vs benchmark

Late-Stage Pipeline

15%

2 trials in Phase 3/4

Results Transparency

50%

5 of 10 completed with results

Key Signals

5 with results83% success

Data Visualizations

Phase Distribution

11Total
P 1 (2)
P 2 (7)
P 4 (2)

Trial Status

Completed10
Terminated2
Withdrawn1

Trial Success Rate

83.3%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (13)

Showing 13 of 13 trials
NCT01363908Phase 2TerminatedPrimary

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

NCT01186419Phase 2CompletedPrimary

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

NCT01927913Phase 2WithdrawnPrimary

Treatment of Iron Overload Requiring Chelation Therapy

NCT00560820Phase 1Completed

Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload

NCT00390858Phase 2CompletedPrimary

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

NCT01326845Phase 4Terminated

Myelodysplastic Syndrome (MDS) Gastrointestinal (GI) Tolerability Study

NCT01044186Phase 2CompletedPrimary

A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity

NCT00673608Phase 4Completed

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

NCT01241357CompletedPrimary

High-Tc Susceptometer to Monitor Transfusional Iron Overload

NCT00379483Phase 2CompletedPrimary

Extension Study of Iron Chelation Therapy With Deferasirox in Patients With Transfusional Iron Overload

NCT00600938Phase 2CompletedPrimary

Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload

NCT01838291CompletedPrimary

Active Drug Surveillance Program of Ferriprox Use

NCT01039636Phase 1CompletedPrimary

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Showing all 13 trials

Research Network

Activity Timeline