Thyroid-Associated Ophthalmopathy
12
2
2
7
Key Insights
Highlights
Success Rate
88% trial completion (above average)
Treatment Research
16 treatments under study, led by Methylprednisolone
Research Leaders
14 sponsors active, led by Haukeland University Hospital
Related Conditions
Often studied with 17 related conditions
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
8.3%
1 terminated out of 12 trials
87.5%
+0.9% vs benchmark
33%
4 trials in Phase 3/4
29%
2 of 7 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 7 completed trials
Clinical Trials (12)
Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO)
Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease
Establishment of Multimodal-multiparametric Progressive Prediction Models for Thyroid Associated Ophthalmopathy
A Study on the Combined Use of Tocilizumab and Flupentixol-Melitracen in the Treatment of Thyroid-Associated Ophthalmopathy
Teprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease
New Treatment for Patients With Temporal Hollowing After Lateral Wall Decompression
Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy
Lanreotide (Somatuline Autogel) in Thyroid-associated Ophthalmopathy Treatment
The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy
99Tc-MDP for Thyroid-Associated Ophthalmopathy
Trial of Rituximab for Graves' Ophthalmopathy
Treatment of Upper Eyelid Retraction Related to Thyroid-associated Ophthalmopathy Using Subconjunctival Triamcinolone Injections
Research Network
Common Treatments
- Methylprednisolone4
- Lanreotide Autogel Formulation Duration Of Treatment 3 Injections 1 Every 28 Days1
- Normal Saline1
- Tocilizumab400mg Combined With Flupentixol Melitracen05mg10mg1
- Sirolimus1
Active Sponsors
- Haukeland University Hospital2
- Rebecca Bahn1
- Sun Yat-sen University1
- Dalian University1
- Medical University of Vienna1
Top Investigators
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China
Zhongsh Ophthalmic Center
Department of Clinical Pharmacology, Medical University of Vienna
Region Skåne, Endokrinologimottagning
University of Bergen
Related Conditions
- Thyroid Eye Disease2
- Graves Disease2
- Graves Ophthalmopathy2
- Dry Eye Syndrome1
- Graves Hyperthyroidism1