Key Insights

Highlights

Success Rate

78% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

11.8%

8 terminated out of 68 trials

Success Rate

77.8%

-8.8% vs benchmark

Late-Stage Pipeline

41%

28 trials in Phase 3/4

Results Transparency

29%

8 of 28 completed with results

Key Signals

8 with results78% success

Data Visualizations

Phase Distribution

55Total
Not Applicable (6)
P 1 (9)
P 2 (12)
P 3 (22)
P 4 (6)

Trial Status

Completed28
Recruiting9
Terminated8
Not Yet Recruiting7
Active Not Recruiting7
Unknown6

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 28 completed trials

Clinical Trials (68)

Showing 20 of 20 trials
NCT05987423Phase 3CompletedPrimary

Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

NCT07720648Phase 3Not Yet RecruitingPrimary

A Phase III Study of KHN939 in Chinese Patients With Moderate-to-Severe Inactive Thyroid Eye Disease

NCT07438405Phase 2RecruitingPrimary

An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

NCT07720635Phase 3Not Yet RecruitingPrimary

A Phase III Study of KHN939 in Chinese Patients With Moderate-to-Severe Active Thyroid Eye Disease

NCT07622368Phase 1RecruitingPrimary

A Study of IBI3031 in Participants With Thyroid Eye Disease

NCT06401044Phase 1RecruitingPrimary

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

NCT06248619Phase 3Active Not RecruitingPrimary

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

NCT07155668Phase 3CompletedPrimary

A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

NCT06557850Phase 1Active Not RecruitingPrimary

A Trial Investigating Lu AG22515 in Adult Participants With Moderate-to-Severe Thyroid Eye Disease

NCT06367517Completed

Tocilizumab in Corticosteroid-Resistant Graves' Orbitopathy (Thyroid Eye Disease)

NCT07623837Not Yet Recruiting

Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)

NCT06625398Phase 3Active Not RecruitingPrimary

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)

NCT06106828Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

NCT06384547Phase 3CompletedPrimary

A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)

NCT06179875Phase 3CompletedPrimary

An Open-label Study (OLE) for Non-responders of VRDN-001-101 (NCT05176639) and VRDN-001-301 (NCT06021054)

NCT05517447Phase 3TerminatedPrimary

Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

NCT06088979Phase 2Active Not RecruitingPrimary

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

NCT04737330Phase 3TerminatedPrimary

A Study of the Efficacy and Safety of Secukinumab 300 mg in Patients With Thyroid Eye Disease (TED)

NCT06625411Phase 3Active Not RecruitingPrimary

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

NCT06467435Phase 1TerminatedPrimary

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

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