Key Insights

Highlights

Success Rate

76% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

12.5%

8 terminated out of 64 trials

Success Rate

75.8%

-10.7% vs benchmark

Late-Stage Pipeline

41%

26 trials in Phase 3/4

Results Transparency

28%

7 of 25 completed with results

Key Signals

7 with results76% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (6)
P 1 (8)
P 2 (12)
P 3 (20)
P 4 (6)

Trial Status

Completed25
Active Not Recruiting9
Terminated8
Recruiting8
Unknown6
Not Yet Recruiting5

Trial Success Rate

75.8%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (64)

Showing 20 of 20 trials
NCT05987423Phase 3Active Not RecruitingPrimary

Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

NCT06384547Phase 3CompletedPrimary

A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)

NCT06179875Phase 3CompletedPrimary

An Open-label Study (OLE) for Non-responders of VRDN-001-101 (NCT05176639) and VRDN-001-301 (NCT06021054)

NCT05517447Phase 3TerminatedPrimary

Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

NCT06088979Phase 2Active Not RecruitingPrimary

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

NCT04737330Phase 3TerminatedPrimary

A Study of the Efficacy and Safety of Secukinumab 300 mg in Patients With Thyroid Eye Disease (TED)

NCT06557850Phase 1Active Not RecruitingPrimary

A Trial Investigating Lu AG22515 in Adult Participants With Moderate-to-Severe Thyroid Eye Disease

NCT06625411Phase 3Active Not RecruitingPrimary

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

NCT06401044Phase 1RecruitingPrimary

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

NCT06467435Phase 1TerminatedPrimary

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

NCT05524571Phase 3CompletedPrimary

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

NCT05012033RecruitingPrimary

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting

NCT06307613Phase 3TerminatedPrimary

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease

NCT06307626Phase 3TerminatedPrimary

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease.

NCT07462130Phase 1Not Yet RecruitingPrimary

An Efficacy and Safety Study of NTB003 in Participants With Thyroid Eye Disease (TED)

NCT06226545Phase 2CompletedPrimary

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

NCT07438405Phase 2Not Yet RecruitingPrimary

An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

NCT07423013Not ApplicableRecruitingPrimary

Evaluating the Efficacy and Safety of Teprotumumab N01 in Patients With Thyroid Eye Disease.

NCT06106828Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

NCT06248619Phase 3Active Not RecruitingPrimary

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

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