Key Insights

Highlights

Success Rate

64% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

18.5%

5 terminated out of 27 trials

Success Rate

64.3%

-22.2% vs benchmark

Late-Stage Pipeline

15%

4 trials in Phase 3/4

Results Transparency

56%

5 of 9 completed with results

Key Signals

5 with results64% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (1)
P 1 (1)
P 2 (8)
P 3 (4)

Trial Status

Completed9
Unknown7
Terminated5
Recruiting3
Withdrawn2
Not Yet Recruiting1

Trial Success Rate

64.3%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT05468320Phase 3CompletedPrimary

Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura

NCT04074187Phase 2CompletedPrimary

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

NCT06727669Recruiting

Longitudinal Cohort of Thrombosis and Hemostasis Diseases

NCT00953771Phase 2TerminatedPrimary

Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP)

NCT01931644Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

NCT03187652RecruitingPrimary

A Prospective Study on the Long-Term Vascular Burden in Thrombotic Thrombocytopenic Purpura Patients

NCT01257269RecruitingPrimary

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)

NCT00713193Phase 3CompletedPrimary

Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP)

NCT05785468UnknownPrimary

A Retrospective, Observational Study on the Response to Caplacizumab Treatment in aTTP Patients: the Italian Experience (ROSCAPLI)

NCT05568147Phase 2Not Yet RecruitingPrimary

Aspirin for Prophylaxis of TTP

NCT05389007UnknownPrimary

.German TTP-Registry (Thrombotic Thrombocytopenic Purpura)

NCT03237819Phase 3UnknownPrimary

Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care

NCT01554514Phase 2CompletedPrimary

Low Dose Rituximab in Thrombotic Thrombocytopenic Purpura

NCT04981028UnknownPrimary

The ConNeCT Study: Neurological Complications of TTP

NCT03369314CompletedPrimary

Observational Study of the Use of octaplasLG®.

NCT04588194Phase 2Unknown

Romiplostim, Rituximab and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia

NCT01938404TerminatedPrimary

Octaplas Adult TTP Trial

NCT02134171Not ApplicableCompleted

Early Predictive Factors of Cardiac and Cerebral Involvement in TMA

NCT02626663Withdrawn

The Role of Microparticles as a Biomarker

NCT03605511UnknownPrimary

TTP and aHUS in Complicated Pregnancies

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Research Network

Activity Timeline