Thrombotic Microangiopathies
25
8
8
5
Key Insights
Highlights
Success Rate
71% trial completion
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 27/100
8.0%
2 terminated out of 25 trials
71.4%
-15.1% vs benchmark
20%
5 trials in Phase 3/4
120%
6 of 5 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 5 completed trials
Clinical Trials (25)
TGD001 Treatment in Thrombotic Microangiopathies
Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura
Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome
Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center
Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium
The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)
Identification of Plasma Biomarkers for Early Diagnosis of Transplant-associated Thrombotic Microangiopathy
TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients
Nomacopan (rVA576) in Transplant Associated Thrombotic Microangiopathy
Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
Longitudinal Cohort of Thrombosis and Hemostasis Diseases
Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies
Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma
Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With Eculizumab
Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients
Automated Surveillance, Alert, and Rapid Diagnosis of Thrombotic Microangiopathies: the ASARD-TMA Study
Multicenter, Uncontrolled Pilot Study Evaluating the Efficacy of Eculizumab in the Treatment of Gemcitabine-induced Thrombotic Microangiopathies
Ravulizumab and COVID-19
Construction of a Database for TMA
Study in Adult and Pediatric Patients With HSCT-TMA