Systemic Sclerosis
313
57
67
144
Key Insights
Highlights
Success Rate
88% trial completion (above average)
Published Results
37 trials with published results (12%)
Research Maturity
144 completed trials (46% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
6.4%
20 terminated out of 313 trials
87.8%
+1.2% vs benchmark
8%
26 trials in Phase 3/4
26%
37 of 144 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 144 completed trials
Clinical Trials (313)
A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc)
A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study
Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH