Systemic Sclerosis
309
59
69
143
Key Insights
Highlights
Success Rate
88% trial completion (above average)
Published Results
37 trials with published results (12%)
Research Maturity
143 completed trials (46% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
6.1%
19 terminated out of 309 trials
88.3%
+1.7% vs benchmark
8%
26 trials in Phase 3/4
26%
37 of 143 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 143 completed trials
Clinical Trials (309)
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
A Study of AZD0120 in Autoimmune Diseases
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic Sclerosis
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study
CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases
Hyaluronidase for Sclerodactyly in Systemic Sclerosis Trial
A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease
Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
Immun4Cure Cohort of Autoimmune Diseases
Prospective Cohort of Patients With Systemic Sclerosis at Brest University Hospital With Biobanking
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
Assessment of Nutritional Status in Systemic Sclerosis