Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

37 trials with published results (12%)

Research Maturity

144 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

6.4%

20 terminated out of 313 trials

Success Rate

87.8%

+1.2% vs benchmark

Late-Stage Pipeline

8%

26 trials in Phase 3/4

Results Transparency

26%

37 of 144 completed with results

Key Signals

37 with results88% success20 terminated

Data Visualizations

Phase Distribution

224Total
Not Applicable (83)
Early P 1 (12)
P 1 (50)
P 2 (53)
P 3 (16)
P 4 (10)

Trial Status

Completed144
Recruiting57
Unknown47
Terminated20
Not Yet Recruiting20
Active Not Recruiting10

Trial Success Rate

87.8%

Benchmark: 86.6%

Based on 144 completed trials

Clinical Trials (313)

Showing 20 of 20 trials
NCT07854483Phase 1Not Yet Recruiting

A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc)

NCT07782450Phase 1Not Yet Recruiting

A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases

NCT07497087Phase 3RecruitingPrimary

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

NCT05925803Phase 3Active Not RecruitingPrimary

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

NCT05785065Phase 2Recruiting

Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease

NCT07038447Phase 1Enrolling By Invitation

A Study of KITE-363 in Participants With Refractory Autoimmune Diseases

NCT07335562Phase 3Not Yet RecruitingPrimary

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

NCT07821398Phase 2Not Yet Recruiting

Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis

NCT03582800Phase 2RecruitingPrimary

Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study

NCT06373263Not ApplicableCompleted

Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1

NCT07085104Phase 1Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

NCT06400303Phase 1TerminatedPrimary

KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

NCT06925542Phase 1Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

NCT06328777Phase 2RecruitingPrimary

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

NCT03630211Phase 2RecruitingPrimary

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

NCT07737470Not Yet Recruiting

Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research

NCT06733935Phase 1RecruitingPrimary

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

NCT07284797Phase 1Recruiting

A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases

NCT05869955Phase 1Active Not Recruiting

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

NCT06947460Phase 1Recruiting

CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH

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