Key Insights

Highlights

Success Rate

79% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.5%

4 terminated out of 32 trials

Success Rate

78.9%

-7.6% vs benchmark

Late-Stage Pipeline

9%

3 trials in Phase 3/4

Results Transparency

47%

7 of 15 completed with results

Key Signals

7 with results79% success

Data Visualizations

Phase Distribution

26Total
Not Applicable (8)
Early P 1 (1)
P 1 (6)
P 2 (8)
P 3 (3)

Trial Status

Completed15
Recruiting5
Terminated4
Not Yet Recruiting3
Active Not Recruiting2
Unknown2

Trial Success Rate

78.9%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (32)

Showing 20 of 20 trials
NCT03816345Phase 1Recruiting

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

NCT05726630Phase 3Active Not RecruitingPrimary

Clinical Study of Divozilimab in Patients With Systemic Scleroderma

NCT01295736Phase 3CompletedPrimary

Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY

NCT03575156Not ApplicableCompleted

Microparticles's Role in the Pathophysiology of Systemic Lupus Erythematosus and Systemic Sclerosis

NCT07502105Not ApplicableNot Yet RecruitingPrimary

Efficacy and Safety of Firsekibart in the Treatment of Systemic Sclerosis

NCT04380831Early Phase 1RecruitingPrimary

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

NCT00318188Not ApplicableCompletedPrimary

Effects of a Personalized Standardized Rehabilitation Program in Systemic Sclerosis

NCT07343115RecruitingPrimary

Familial Systemic Scleroderma

NCT07090226Not ApplicableRecruitingPrimary

Diffuse Cutaneous Scleroderma (DSSc) SFDI Study

NCT05672992Not ApplicableActive Not RecruitingPrimary

Longitudinal Spatial Frequency Domain Imaging Study

NCT07326033Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclEroderma

NCT03816189Completed

Role of Eosinophil in Fibrogenesis of Systemic Sclerosis

NCT07251179Not Yet Recruiting

Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies

NCT01413100Phase 2CompletedPrimary

Scleroderma Treatment With Autologous Transplant (STAT) Study

NCT02213705Phase 1CompletedPrimary

Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem Cells

NCT01559129Phase 2Terminated

Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease

NCT06056921Phase 1Recruiting

Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease

NCT03262922CompletedPrimary

Clinical and Paraclinical Characteristics of the Systemic Scleroderma Cohort According to the Criteria ACR 2013 and the History of Professional Exposure or of Agricultural Environment

NCT03508375Not ApplicableUnknownPrimary

Evaluation of the Serum Soluble Fractalkine as a Biomarker of Pulmonary Fibrosis in Systemic Sclerosis

NCT00697736Not ApplicableCompletedPrimary

Cardiac Repercussion of Systemic Sclerodermias

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