Key Insights

Highlights

Success Rate

69% trial completion

Published Results

35 trials with published results (32%)

Research Maturity

63 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

25.5%

28 terminated out of 110 trials

Success Rate

69.2%

-17.3% vs benchmark

Late-Stage Pipeline

2%

2 trials in Phase 3/4

Results Transparency

56%

35 of 63 completed with results

Key Signals

35 with results69% success28 terminated

Data Visualizations

Phase Distribution

108Total
Not Applicable (5)
Early P 1 (2)
P 1 (36)
P 2 (63)
P 3 (2)

Trial Status

Completed63
Terminated28
Withdrawn8
Unknown5
Active Not Recruiting5
Not Yet Recruiting1

Trial Success Rate

69.2%

Benchmark: 86.5%

Based on 63 completed trials

Clinical Trials (110)

Showing 20 of 20 trials
NCT06416085Phase 2Active Not Recruiting

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer

NCT05176470Phase 1Active Not Recruiting

Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients

NCT07376317Phase 2Active Not Recruiting

Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS)

NCT03235245Phase 2Active Not Recruiting

Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib

NCT04356729Phase 2Active Not Recruiting

A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma

NCT01703507Phase 1Completed

Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma

NCT02145910Phase 1Withdrawn

Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases

NCT03200847Phase 1CompletedPrimary

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

NCT00655655Phase 1Completed

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

NCT02107755Phase 2Completed

Stereotactic Radiation Therapy and Ipilimumab in Treating Patients With Metastatic Melanoma

NCT00199342Phase 1TerminatedPrimary

A Study of a Monoclonal Antibody, KW-2871, in Patients With Advanced Melanoma

NCT00003552Phase 1TerminatedPrimary

Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Melanoma

NCT00019448Phase 2CompletedPrimary

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma

NCT00019396Phase 2CompletedPrimary

flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer

NCT00019890Phase 2CompletedPrimary

Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma

NCT00979693Phase 2Withdrawn

Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma

NCT06093594Not Yet RecruitingPrimary

Investigating Participation Patterns Among Stage IV Melanoma Patients

NCT04670445Not ApplicableUnknownPrimary

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

NCT04059224Phase 2CompletedPrimary

TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma

NCT02203604Phase 2Terminated

High-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By Surgery

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Research Network

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