Key Insights

Highlights

Success Rate

75% trial completion

Published Results

84 trials with published results (42%)

Research Maturity

129 completed trials (64% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

20.8%

42 terminated out of 202 trials

Success Rate

75.4%

-11.1% vs benchmark

Late-Stage Pipeline

4%

8 trials in Phase 3/4

Results Transparency

65%

84 of 129 completed with results

Key Signals

84 with results75% success42 terminated

Data Visualizations

Phase Distribution

197Total
Not Applicable (28)
Early P 1 (7)
P 1 (81)
P 2 (73)
P 3 (8)

Trial Status

Completed129
Terminated42
Withdrawn13
Active Not Recruiting7
Unknown6
Recruiting5

Trial Success Rate

75.4%

Benchmark: 86.5%

Based on 129 completed trials

Clinical Trials (202)

Showing 20 of 20 trials
NCT03971409Phase 2Active Not Recruiting

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

NCT02860000Phase 2Completed

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

NCT02157051Phase 1Active Not Recruiting

Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer

NCT02226276Not ApplicableActive Not Recruiting

Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer

NCT06678269Phase 1Recruiting

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

NCT01881048Early Phase 1Completed

Window of Opportunity Study Targeting the Inflammatory Milieu

NCT01093612Not ApplicableActive Not Recruiting

Positron Emission Tomography in Women With Advanced HER2-Positive Breast Cancer

NCT05840211Phase 3Active Not Recruiting

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

NCT05959291Not ApplicableRecruiting

Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer

NCT06439693Phase 2Recruiting

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

NCT01730833Phase 2Active Not Recruiting

Pertuzumab, Trastuzumab, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With HER2-Positive Advanced Breast Cancer

NCT01938833Phase 1Terminated

Romidepsin and Abraxane in Treating Patients With Metastatic Inflammatory Breast Cancer

NCT01349088Phase 1Withdrawn

Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer

NCT00436254Phase 1Completed

Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer

NCT00520975Phase 3Terminated

Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU

NCT03154190Not ApplicableCompleted

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

NCT01897441Not ApplicableTerminated

Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer

NCT03206203Phase 2Completed

Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer

NCT04985357Withdrawn

Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs

NCT03683147Not ApplicableCompletedPrimary

Mindfulness-Based Stress Reduction in Helping Participants With Metastatic Breast Cancer

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