Key Insights

Highlights

Success Rate

58% trial completion

Published Results

14 trials with published results (64%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

36.4%

8 terminated out of 22 trials

Success Rate

57.9%

-28.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

127%

14 of 11 completed with results

Key Signals

14 with results58% success

Data Visualizations

Phase Distribution

22Total
Not Applicable (2)
Early P 1 (1)
P 1 (4)
P 2 (15)

Trial Status

Completed11
Terminated8
Withdrawn3

Trial Success Rate

57.9%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT06190249Phase 1Withdrawn

Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma

NCT02203604Phase 2Terminated

High-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By Surgery

NCT01127451Phase 2CompletedPrimary

Study of Denileukin Diftitox in Participants With Stage IIIC and Stage IV Melanoma

NCT02296112Phase 2Completed

Trametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 Mutations

NCT01321437Phase 2Completed

Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanoma

NCT02094872Phase 2Completed

Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic

NCT01748747Early Phase 1Completed

Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery

NCT02166255Phase 1Completed

APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

NCT01533948Phase 2Terminated

Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery

NCT01701037Phase 2Terminated

Dabrafenib Alone and in Combination With Trametinib Before Surgery in Treating Patients With Locally or Regionally Advanced Melanoma That Can Be Removed By Surgery

NCT02236546Not ApplicableTerminated

FDG-PET in Advanced Melanoma

NCT01026324Phase 1Terminated

Dinaciclib in Treating Patients With Stage III-IV Melanoma

NCT00003895Phase 2Completed

Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma

NCT01316692Phase 2Terminated

Aurora A Kinase Inhibitor MLN8237 in Treating Patients With Unresectable Stage III-IV Melanoma

NCT02507076Not ApplicableWithdrawn

Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma

NCT00089063Phase 2Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients Who Have Undergone Surgery for Melanoma

NCT00470470Phase 2Completed

Imatinib Mesylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT01835184Phase 1Terminated

Cabozantinib-S-Malate and Vemurafenib in Treating Patients With Solid Tumors or Melanoma That is Metastatic or That Cannot Be Removed By Surgery

NCT01519427Phase 2Terminated

Selumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib

NCT00085189Phase 2Completed

Vaccine Therapy in Treating Patients With Stage IIC-IV Melanoma

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