Key Insights

Highlights

Success Rate

72% trial completion

Published Results

31 trials with published results (37%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

21.4%

18 terminated out of 84 trials

Success Rate

71.9%

-14.6% vs benchmark

Late-Stage Pipeline

6%

5 trials in Phase 3/4

Results Transparency

67%

31 of 46 completed with results

Key Signals

31 with results72% success18 terminated

Data Visualizations

Phase Distribution

81Total
Not Applicable (13)
Early P 1 (2)
P 1 (34)
P 2 (27)
P 3 (5)

Trial Status

Completed46
Terminated18
Withdrawn8
Active Not Recruiting6
Unknown3
Not Yet Recruiting2

Trial Success Rate

71.9%

Benchmark: 86.5%

Based on 46 completed trials

Clinical Trials (84)

Showing 20 of 20 trials
NCT02495896Phase 1Active Not Recruiting

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

NCT03433469Phase 2Active Not Recruiting

Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgery

NCT01345851Not ApplicableActive Not Recruiting

Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

NCT03366766Phase 2Terminated

Nivolumab Plus Cisplatin/Pemetrexed or Cisplatin/Gemcitabine as Induction in Resectable Non-Small Cell Lung Cancer

NCT05167487RecruitingPrimary

Pathological Response After Neoadjuvant Treatment on NSCLC

NCT02621398Phase 1Completed

Pembrolizumab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-IIIB Non-Small Cell Lung Cancer

NCT03916419Phase 2Completed

Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB, IIIA, and Select IIIB and IIIC Non-small Cell Lung Cancer

NCT02823990Phase 2Completed

TG4010 and Nivolumab in Patients With Lung Cancer

NCT03049618Phase 2Completed

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

NCT02186847Phase 2Completed

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

NCT01737502Phase 1Completed

Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

NCT02819024Not ApplicableCompleted

Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography

NCT05894889Phase 2Active Not Recruiting

Pembrolizumab and Chemotherapy Neoadjuvant/Adjuvant of NSCLC

NCT04062708Phase 2Active Not RecruitingPrimary

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

NCT07043907Phase 2Not Yet RecruitingPrimary

PANK-003 Cell Injection Combined With Standard Adjuvant Chemotherapy After Surgery in Patients With Stage IIIA NSCLC

NCT02262325Phase 2Completed

Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery

NCT02245100Completed

Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer

NCT04776447Phase 2Active Not Recruiting

Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO)

NCT03154190Not ApplicableCompleted

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

NCT02364609Phase 1Completed

Pembrolizumab and Afatinib in Patients With Non-small Cell Lung Cancer With Resistance to Erlotinib

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