Key Insights

Highlights

Success Rate

71% trial completion

Published Results

66 trials with published results (45%)

Research Maturity

88 completed trials (59% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

24.3%

36 terminated out of 148 trials

Success Rate

71.0%

-15.5% vs benchmark

Late-Stage Pipeline

7%

10 trials in Phase 3/4

Results Transparency

75%

66 of 88 completed with results

Key Signals

66 with results71% success36 terminated

Data Visualizations

Phase Distribution

143Total
Not Applicable (50)
Early P 1 (4)
P 1 (33)
P 2 (46)
P 3 (10)

Trial Status

Completed88
Terminated36
Active Not Recruiting14
Withdrawn7
Unknown3

Trial Success Rate

71.0%

Benchmark: 86.5%

Based on 88 completed trials

Clinical Trials (148)

Showing 20 of 20 trials
NCT02488967Phase 3Active Not Recruiting

Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

NCT02957968Phase 2Active Not Recruiting

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

NCT03971409Phase 2Active Not Recruiting

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

NCT02445391Phase 3Active Not Recruiting

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

NCT01525966Phase 2Active Not Recruiting

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer

NCT02860000Phase 2Completed

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

NCT03414970Phase 3Active Not Recruiting

Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

NCT02157051Phase 1Active Not Recruiting

Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer

NCT00066690Phase 3Completed

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

NCT01881048Early Phase 1Completed

Window of Opportunity Study Targeting the Inflammatory Milieu

NCT01953588Phase 3Active Not Recruiting

Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery

NCT02760030Phase 2Completed

Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgery

NCT01750073Phase 2Active Not Recruiting

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

NCT02827877Phase 2Active Not Recruiting

Cu64-DOTA-trastuzumab PET and Markers Predicting Response to Neoadjuvant Trastuzumab + Pertuzum in HER2+ Breast Cancer

NCT03284346Not ApplicableTerminated

Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors

NCT02400060Not ApplicableCompleted

Telephone-Based Intervention in Increasing Adherence to Adjuvant Hormonal Therapy in Patients With Breast Cancer

NCT01730833Phase 2Active Not Recruiting

Pertuzumab, Trastuzumab, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With HER2-Positive Advanced Breast Cancer

NCT01824836Not ApplicableActive Not Recruiting

A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

NCT03188393Phase 2Completed

Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

NCT01818063Phase 2Completed

Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer

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Research Network

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