Key Insights

Highlights

Success Rate

81% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

15.6%

5 terminated out of 32 trials

Success Rate

80.8%

-5.7% vs benchmark

Late-Stage Pipeline

9%

3 trials in Phase 3/4

Results Transparency

33%

7 of 21 completed with results

Key Signals

7 with results81% success

Data Visualizations

Phase Distribution

29Total
P 1 (10)
P 2 (16)
P 3 (3)

Trial Status

Completed21
Terminated5
Unknown2
Withdrawn2
Recruiting1
Active Not Recruiting1

Trial Success Rate

80.8%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (32)

Showing 20 of 20 trials
NCT07302607RecruitingPrimary

Predictive Factors of Complete Response to Immunotherapy in Metastatic Melanoma: a Single-center Retrospective Study Between 2013 and 2021

NCT03719131Phase 2Active Not Recruiting

Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy

NCT03200847Phase 1Completed

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

NCT05079113CompletedPrimary

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

NCT00019890Phase 2Completed

Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma

NCT04059224Phase 2Completed

TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma

NCT04703426Phase 2Withdrawn

Sargramostim (GM-CSF) + PD-1

NCT00945269Phase 1Terminated

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

NCT03385486Phase 1UnknownPrimary

Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors

NCT01726738Phase 2CompletedPrimary

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

NCT02073123Phase 1Completed

Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma

NCT02676869Phase 1Completed

Phase 1 Study of IMP321 (Eftilagimod Alpha) Adjuvant to Anti-PD-1 Therapy in Unresectable or Metastatic Melanoma

NCT01107665Phase 2CompletedPrimary

Pazopanib and Paclitaxel as First-Line Treatment for Subjects With Unresectable Stage III and Stage IV Melanoma

NCT02306850Phase 2Completed

Neoadjuvant Pembrolizumab for Unresectable Stage III and Unresectable Stage IV Melanoma

NCT01875653Phase 3Terminated

Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma

NCT00074308Phase 1Completed

Imatinib Mesylate and Bevacizumab in Treating Patients With Advanced Melanoma or Other Advanced Cancers

NCT00450255Phase 2Completed

VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT02794636CompletedPrimary

Interferon Toxicities in Melanoma Treatment

NCT01376713Phase 2CompletedPrimary

Anti-CD20 (Cluster of Differentiation Antigen 20) Therapy to Treat Metastatic Melanoma

NCT01851408Phase 2Withdrawn

Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

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