Squamous Cell Carcinoma of the Head and Neck
180
11
21
92
Key Insights
Highlights
Success Rate
69% trial completion
Published Results
55 trials with published results (31%)
Research Maturity
92 completed trials (51% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 74/100
22.8%
41 terminated out of 180 trials
69.2%
-17.4% vs benchmark
9%
16 trials in Phase 3/4
60%
55 of 92 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 92 completed trials
Clinical Trials (180)
Hypofractionated Radiotherapy in Older Adults With Head and Neck Squamous Cell Carcinoma
Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer
Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
A Study to Evaluate MRG003 vs Cetuximab/Methotrexate in in the Treatment of Patients With RM-SCCHN
Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer
Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma
CIML NK Cell in Head & Neck Cancer
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
VX15/2503 in Combination With Ipilimumab or Nivolumab in Patients With Head and Neck Cancer
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors
Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck
Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.
Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies
Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study
A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors