Key Insights

Highlights

Success Rate

66% trial completion

Published Results

19 trials with published results (13%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.5%

22 terminated out of 142 trials

Success Rate

66.2%

-20.4% vs benchmark

Late-Stage Pipeline

8%

11 trials in Phase 3/4

Results Transparency

44%

19 of 43 completed with results

Key Signals

19 with results66% success22 terminated

Data Visualizations

Phase Distribution

133Total
Not Applicable (19)
Early P 1 (4)
P 1 (61)
P 2 (38)
P 3 (9)
P 4 (2)

Trial Status

Completed43
Recruiting34
Terminated22
Active Not Recruiting19
Withdrawn10
Unknown7

Trial Success Rate

66.2%

Benchmark: 86.6%

Based on 43 completed trials

Clinical Trials (142)

Showing 20 of 20 trials
NCT07509099Phase 3RecruitingPrimary

Cetuximab Combined With Pembrolizumab or Finotonlimab and Chemotherapy in R/M HNSCC

NCT03576417Phase 3Active Not RecruitingPrimary

A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck

NCT07823309Not ApplicableNot Yet Recruiting

Quad Shot Versus Split Course Radiotherapy in Incurable Head and Neck Cancer

NCT05816785Early Phase 1Completed

Pilot Study of Imatinib Cetuximab Combo for H & N Cancer

NCT05007106Phase 2Completed

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

NCT07219212Phase 1RecruitingPrimary

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT06385080Phase 1RecruitingPrimary

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

NCT07276399Phase 3RecruitingPrimary

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

NCT06236425Phase 1CompletedPrimary

TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC

NCT05952934Phase 2RecruitingPrimary

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

NCT06487403Not ApplicableRecruitingPrimary

HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers

NCT06557889Phase 2Active Not RecruitingPrimary

Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas

NCT05935995Not ApplicableCompletedPrimary

Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination

NCT05668858Phase 1Active Not RecruitingPrimary

A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

NCT04895709Phase 1Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

NCT06242470Phase 1Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT06515990Phase 1Recruiting

A Study of DM005 in Patients With Advanced Solid Tumors

NCT06085781Not ApplicableRecruitingPrimary

A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers

NCT04747054Phase 3RecruitingPrimary

Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers

NCT06367257Not ApplicableRecruitingPrimary

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy

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