Key Insights

Highlights

Success Rate

81% trial completion

Published Results

127 trials with published results (17%)

Research Maturity

421 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

13.2%

101 terminated out of 764 trials

Success Rate

80.7%

-5.9% vs benchmark

Late-Stage Pipeline

2%

15 trials in Phase 3/4

Results Transparency

30%

127 of 421 completed with results

Key Signals

127 with results81% success101 terminated

Data Visualizations

Phase Distribution

721Total
Not Applicable (16)
Early P 1 (10)
P 1 (604)
P 2 (76)
P 3 (10)
P 4 (5)

Trial Status

Completed421
Terminated101
Recruiting86
Unknown48
Active Not Recruiting41
Not Yet Recruiting30

Trial Success Rate

80.7%

Benchmark: 86.5%

Based on 421 completed trials

Clinical Trials (764)

Showing 20 of 20 trials
NCT07509034Phase 1Not Yet Recruiting

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

NCT03486873Phase 3RecruitingPrimary

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT01445509Phase 1CompletedPrimary

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

NCT07639801Not ApplicableNot Yet Recruiting

68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors

NCT07522073Phase 3RecruitingPrimary

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

NCT00489307Phase 2Active Not RecruitingPrimary

Dexamethasone for Symptom Burden in Advanced Cancer Patients

NCT07631611CompletedPrimary

Organ-Specific Differences in Immunotherapy Response Among Metastatic Cancer Patients

NCT02154022Enrolling By Invitation

Collection of Pharmacokinetic Samples From People With Unanticipated Response, Significant Toxicity or Concern of Future Toxicity

NCT07631871Phase 2Not Yet Recruiting

An Exploratory Study of Zanidatamab in HER2-positive Advanced Tumor After at Least One Line of Standard Therapy

NCT07631884Phase 2Not Yet RecruitingPrimary

Exploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of HER2-Expressiong Advanced Solid Tumor

NCT02423057Phase 1Completed

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

NCT03366116Phase 1Recruiting

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

NCT05503797Phase 2Recruiting

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

NCT07395258Phase 1SuspendedPrimary

A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

NCT07038369Phase 1Active Not Recruiting

A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

NCT07624864Phase 1Not Yet RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, PK and Efficacy of Hemay5087 in Patients With Advanced Solid Tumors

NCT04303858Phase 1TerminatedPrimary

A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid Tumors

NCT07416123Phase 1RecruitingPrimary

A Study of GEN1106 in Participants With Solid Tumors

NCT07621471Early Phase 1Not Yet RecruitingPrimary

IL-15 Enhanced NK Cell Therapy for Solid Tumors

NCT05536141Phase 1Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

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