Key Insights

Highlights

Success Rate

81% trial completion

Published Results

131 trials with published results (17%)

Research Maturity

423 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

13.3%

102 terminated out of 769 trials

Success Rate

80.6%

-6.0% vs benchmark

Late-Stage Pipeline

2%

15 trials in Phase 3/4

Results Transparency

31%

131 of 423 completed with results

Key Signals

131 with results81% success102 terminated

Data Visualizations

Phase Distribution

726Total
Not Applicable (18)
Early P 1 (11)
P 1 (605)
P 2 (77)
P 3 (10)
P 4 (5)

Trial Status

Completed423
Terminated102
Recruiting85
Unknown47
Active Not Recruiting41
Not Yet Recruiting33

Trial Success Rate

80.6%

Benchmark: 86.5%

Based on 423 completed trials

Clinical Trials (769)

Showing 20 of 20 trials
NCT07509034Phase 1Not Yet Recruiting

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

NCT07492680Phase 2RecruitingPrimary

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

NCT01875601Phase 1CompletedPrimary

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

NCT03486873Phase 3RecruitingPrimary

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT04337177Phase 1Active Not RecruitingPrimary

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT06710132Phase 1Active Not RecruitingPrimary

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

NCT01445509Phase 1CompletedPrimary

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

NCT05536141Phase 1Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

NCT06915753Phase 1Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

NCT02379416Phase 1CompletedPrimary

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

NCT02423057Phase 1Completed

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

NCT07415031Phase 2RecruitingPrimary

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

NCT07727317Not ApplicableNot Yet RecruitingPrimary

Evaluate the Diagnostic Efficacy and Safety of INR 202 PET/CT Imaging in Participants With Advanced Solid Tumors

NCT05503797Phase 2Recruiting

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

NCT07231211Phase 1RecruitingPrimary

A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors

NCT04570423Phase 2RecruitingPrimary

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

NCT07002203Phase 1RecruitingPrimary

Personalized Neoantigen Peptide Vaccines for Solid Tumors

NCT07522073Phase 3RecruitingPrimary

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

NCT07689812Not ApplicableNot Yet Recruiting

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

NCT07374848Phase 1RecruitingPrimary

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

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