Key Insights

Highlights

Success Rate

74% trial completion

Published Results

54 trials with published results (18%)

Research Maturity

106 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.5%

37 terminated out of 296 trials

Success Rate

74.1%

-12.4% vs benchmark

Late-Stage Pipeline

6%

18 trials in Phase 3/4

Results Transparency

51%

54 of 106 completed with results

Key Signals

54 with results74% success37 terminated

Data Visualizations

Phase Distribution

261Total
Not Applicable (42)
Early P 1 (8)
P 1 (90)
P 2 (103)
P 3 (15)
P 4 (3)

Trial Status

Completed106
Recruiting62
Unknown42
Terminated37
Active Not Recruiting27
Withdrawn13

Trial Success Rate

74.1%

Benchmark: 86.5%

Based on 106 completed trials

Clinical Trials (296)

Showing 20 of 20 trials
NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT04040205Phase 2Recruiting

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT05264974Phase 1Recruiting

Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

NCT02923778Phase 2Active Not Recruiting

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

NCT06660810Phase 2Active Not RecruitingPrimary

Neoadjuvant Intralesional Injection of Talimogene Laherparepvec

NCT05000294Phase 1Recruiting

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

NCT04946357Not ApplicableActive Not RecruitingPrimary

Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions

NCT05109494Phase 2SuspendedPrimary

Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

NCT04037527Phase 1TerminatedPrimary

Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities

NCT03972930Phase 2Active Not RecruitingPrimary

Hypofractionated Radiotherapy for Soft Tissue Sarcomas

NCT07514819Not ApplicableNot Yet Recruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT05712694Phase 3TerminatedPrimary

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

NCT03818412Not ApplicableRecruitingPrimary

Circulating Tumor DNA in Soft Tissue Sarcoma

NCT05526417Not ApplicableRecruitingPrimary

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

NCT03508726Phase 1CompletedPrimary

High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas

NCT04616248Phase 1Active Not Recruiting

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

NCT07261631Phase 1Recruiting

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

NCT03462316Phase 1Completed

NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma

NCT04589741Phase 2RecruitingPrimary

Toripalimab Combined With CAV/IE Regimen

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