Key Insights

Highlights

Success Rate

73% trial completion

Published Results

54 trials with published results (18%)

Research Maturity

106 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.5%

40 terminated out of 296 trials

Success Rate

72.6%

-14.0% vs benchmark

Late-Stage Pipeline

6%

18 trials in Phase 3/4

Results Transparency

51%

54 of 106 completed with results

Key Signals

54 with results73% success40 terminated

Data Visualizations

Phase Distribution

261Total
Not Applicable (42)
Early P 1 (8)
P 1 (90)
P 2 (103)
P 3 (15)
P 4 (3)

Trial Status

Completed106
Recruiting60
Unknown41
Terminated40
Active Not Recruiting27
Withdrawn13

Trial Success Rate

72.6%

Benchmark: 86.6%

Based on 106 completed trials

Clinical Trials (296)

Showing 20 of 20 trials
NCT04969835Phase 1Active Not Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

NCT00718484Phase 2TerminatedPrimary

A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sarcoma

NCT01168791Phase 3TerminatedPrimary

Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue Sarcoma

NCT02923778Phase 2Active Not Recruiting

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

NCT05264974Phase 1Suspended

Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

NCT05821231Phase 1CompletedPrimary

Study Evaluating the Safety and Efficacy of MEDI5752 in Combination With Stereotactic Radiotherapy in Patients With Metastatic Sarcoma

NCT04577014Phase 1RecruitingPrimary

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

NCT05813327Phase 1TerminatedPrimary

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

NCT04307277Phase 3RecruitingPrimary

Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT07514819Not ApplicableRecruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT02672527Phase 3CompletedPrimary

Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma

NCT05621668Phase 1Active Not RecruitingPrimary

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

NCT06537596Phase 1RecruitingPrimary

89Zr-olaratumab Dosimetry in Participants With PDGFR Alpha Positive Solid Tumours and Soft Tissue Sarcoma

NCT06409013Recruiting

Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT04040205Phase 2Recruiting

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

NCT06660810Phase 2Active Not RecruitingPrimary

Neoadjuvant Intralesional Injection of Talimogene Laherparepvec

NCT05000294Phase 1Recruiting

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

NCT04946357Not ApplicableActive Not RecruitingPrimary

Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions

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