Key Insights

Highlights

Success Rate

75% trial completion

Published Results

54 trials with published results (18%)

Research Maturity

106 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.2%

36 terminated out of 296 trials

Success Rate

74.6%

-11.9% vs benchmark

Late-Stage Pipeline

6%

18 trials in Phase 3/4

Results Transparency

51%

54 of 106 completed with results

Key Signals

54 with results75% success36 terminated

Data Visualizations

Phase Distribution

261Total
Not Applicable (42)
Early P 1 (8)
P 1 (90)
P 2 (103)
P 3 (15)
P 4 (3)

Trial Status

Completed106
Recruiting64
Unknown42
Terminated36
Active Not Recruiting26
Withdrawn13

Trial Success Rate

74.6%

Benchmark: 86.5%

Based on 106 completed trials

Clinical Trials (296)

Showing 20 of 20 trials
NCT03462316Phase 1Completed

NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma

NCT03890068Phase 2CompletedPrimary

Anlotinib Maintenance Treatment for Advanced Soft Tissue Sarcoma

NCT05549921Phase 2TerminatedPrimary

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

NCT04589741Phase 2RecruitingPrimary

Toripalimab Combined With CAV/IE Regimen

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT03719430Phase 2CompletedPrimary

APX005M and Doxorubicin in Advanced Sarcoma

NCT06087861Phase 2RecruitingPrimary

5-Day Preoperative Radiation for Soft Tissue Sarcoma

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT05000294Phase 1Recruiting

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

NCT06022159Phase 2RecruitingPrimary

A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.

NCT07609329Not ApplicableRecruiting

Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas

NCT05264974Phase 1Suspended

Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

NCT04634227Early Phase 1Active Not Recruiting

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

NCT03114527Phase 2Active Not RecruitingPrimary

Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

NCT07049848Phase 2RecruitingPrimary

SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma

NCT04055753Active Not RecruitingPrimary

Study to Assess TOPO2A as a Biomarker for Sensitivity to Doxorubicin/Doxil in Soft Tissue Sarcoma

NCT03449108Phase 2Active Not Recruiting

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

NCT05301764Phase 1CompletedPrimary

A Study of LVGN6051 Combined With Anlotinib in Patient With Soft Tissue Sarcoma

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT06129903Not ApplicableRecruiting

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

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