Key Insights

Highlights

Success Rate

96% trial completion (above average)

Published Results

20 trials with published results (34%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

3.4%

2 terminated out of 58 trials

Success Rate

96.1%

+9.6% vs benchmark

Late-Stage Pipeline

14%

8 trials in Phase 3/4

Results Transparency

41%

20 of 49 completed with results

Key Signals

20 with results96% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (1)
P 1 (21)
P 2 (22)
P 3 (6)
P 4 (2)

Trial Status

Completed49
Withdrawn2
Terminated2
Unknown2
Recruiting2
Active Not Recruiting1

Trial Success Rate

96.1%

Benchmark: 86.5%

Based on 49 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT04957485Phase 2Active Not RecruitingPrimary

Study to Assess the Safety and Immunogenicity of TPOXX® When Administered Orally for 28 Days With JYNNEOS

NCT07379580Phase 2Recruiting

A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa

NCT07377175Phase 1RecruitingPrimary

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BSY001 After Single/Multiple Doses.

NCT00437021Phase 1CompletedPrimary

MVA Post-Event: Administration Timing and Boost Study

NCT05995275Phase 1CompletedPrimary

A Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared With Placebo in Healthy Participants From ≥18 Years of Age to <50 Years of Age

NCT00879762Phase 2CompletedPrimary

High Dose IMVAMUNE® in Vaccinia-Naive Individuals

NCT02080767UnknownPrimary

Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure

NCT05935917Phase 1CompletedPrimary

Study Evaluating the Bioequivalence of Brincidofovir Form H and Form II Tablets in Healthy Adults

NCT04485039Phase 4CompletedPrimary

Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders

NCT04971109Phase 3CompletedPrimary

Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Days

NCT04392739Phase 4CompletedPrimary

Safety, Tolerability and PK of TPOXX in Adults Weighing More Than 120 KG

NCT00928577CompletedPrimary

Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®)

NCT00053495Phase 2CompletedPrimary

Effect of Dose, Safety, Tolerability of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination

NCT01540929CompletedPrimary

Post-licensure Department of Defense (DOD) Screening Accuracy Study in Military Personnel

NCT00927719CompletedPrimary

Safety Surveillance Study of ACAM2000® Vaccinia Vaccine

NCT00053482Phase 2CompletedPrimary

Dose Study of ACAM2000 Smallpox Vaccine in Previously Vaccinated Adults

NCT05976100Phase 1CompletedPrimary

Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years

NCT05846243Phase 2CompletedPrimary

Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years

NCT05762523Phase 1CompletedPrimary

Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years

NCT03972111WithdrawnPrimary

A Phase 4, Observational Field Study to Evaluate TPOXX in Patients With Smallpox

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