Key Insights

Highlights

Success Rate

52% trial completion

Published Results

13 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

16.9%

20 terminated out of 118 trials

Success Rate

52.4%

-34.1% vs benchmark

Late-Stage Pipeline

11%

13 trials in Phase 3/4

Results Transparency

59%

13 of 22 completed with results

Key Signals

13 with results52% success20 terminated

Data Visualizations

Phase Distribution

99Total
Not Applicable (12)
P 1 (39)
P 2 (35)
P 3 (13)

Trial Status

Recruiting35
Completed22
Terminated20
Unknown18
Active Not Recruiting17
Not Yet Recruiting4

Trial Success Rate

52.4%

Benchmark: 86.5%

Based on 22 completed trials

Clinical Trials (118)

Showing 20 of 20 trials
NCT05957510Phase 2RecruitingPrimary

Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment

NCT07005128Phase 3RecruitingPrimary

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

NCT04745689Phase 2Active Not RecruitingPrimary

Study of AZD2811 + Durvalumab in ES-SCLC

NCT07218146Phase 3RecruitingPrimary

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

NCT07545954Phase 1Not Yet RecruitingPrimary

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

NCT06449209Phase 2Active Not Recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

NCT05616624Phase 1Active Not Recruiting

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

NCT03540420Phase 2Active Not RecruitingPrimary

Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer

NCT03923270Phase 1Active Not Recruiting

Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer

NCT05578326Phase 2Recruiting

Study of Trilaciclib and Lurbinectidin

NCT06424067Phase 2Recruiting

Phase 2 Study of Fingolimod in Lung Cancers

NCT04234113Phase 1Terminated

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

NCT04450043Not ApplicableActive Not Recruiting

The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance

NCT06957314Not ApplicableRecruitingPrimary

A Study of Hospital-at-Home for People Receiving Tarlatamab

NCT07468656Not Yet RecruitingPrimary

SCLC Tarlatamab Blood Collection

NCT05091567Phase 3Active Not RecruitingPrimary

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

NCT04170946Phase 1Recruiting

Talazoparib and Thoracic RT for ES-SCLC

NCT05068232Phase 2RecruitingPrimary

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

NCT04471727Phase 1Active Not RecruitingPrimary

A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)

NCT07050472CompletedPrimary

Durvalumab After Concurrent Chemoradiotherapy (cCRT) for Limited-stage Small-cell Lung Cancer (LS-SCLC)

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