Key Insights

Highlights

Success Rate

51% trial completion

Published Results

13 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

18.2%

22 terminated out of 121 trials

Success Rate

51.1%

-35.4% vs benchmark

Late-Stage Pipeline

12%

14 trials in Phase 3/4

Results Transparency

57%

13 of 23 completed with results

Key Signals

13 with results51% success22 terminated

Data Visualizations

Phase Distribution

102Total
Not Applicable (12)
P 1 (40)
P 2 (36)
P 3 (14)

Trial Status

Recruiting34
Completed23
Terminated22
Unknown18
Active Not Recruiting17
Not Yet Recruiting5

Trial Success Rate

51.1%

Benchmark: 86.6%

Based on 23 completed trials

Clinical Trials (121)

Showing 20 of 20 trials
NCT07468656Not Yet RecruitingPrimary

SCLC Tarlatamab Blood Collection

NCT06486428Active Not RecruitingPrimary

Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

NCT07545954Phase 1RecruitingPrimary

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

NCT05957510Phase 2Active Not RecruitingPrimary

Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment

NCT05616624Phase 1Terminated

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

NCT06022757Phase 1Terminated

Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)

NCT07218146Phase 3RecruitingPrimary

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

NCT07625644Phase 3Not Yet Recruiting

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

NCT07005128Phase 3RecruitingPrimary

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

NCT07174583Phase 1RecruitingPrimary

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

NCT06103682Not ApplicableRecruiting

LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)

NCT04745689Phase 2Active Not RecruitingPrimary

Study of AZD2811 + Durvalumab in ES-SCLC

NCT05091567Phase 3Active Not RecruitingPrimary

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

NCT06957314Not ApplicableRecruitingPrimary

A Study of Hospital-at-Home for People Receiving Tarlatamab

NCT05419076Phase 2Recruiting

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

NCT07623369Phase 1Not Yet Recruiting

A First-in-Human Study of HH160 in Patients With Advanced Solid Tumors

NCT05800587Phase 2Recruiting

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

NCT07583511Phase 2RecruitingPrimary

Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled Study

NCT04010357Phase 2CompletedPrimary

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

NCT03583528Active Not Recruiting

DOTATOC PET/CT for Imaging NET Patients

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