Key Insights

Highlights

Success Rate

53% trial completion

Published Results

13 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

17.9%

22 terminated out of 123 trials

Success Rate

53.2%

-33.4% vs benchmark

Late-Stage Pipeline

11%

14 trials in Phase 3/4

Results Transparency

52%

13 of 25 completed with results

Key Signals

13 with results53% success22 terminated

Data Visualizations

Phase Distribution

104Total
Not Applicable (12)
P 1 (40)
P 2 (38)
P 3 (14)

Trial Status

Recruiting36
Completed25
Terminated22
Unknown18
Active Not Recruiting17
Not Yet Recruiting3

Trial Success Rate

53.2%

Benchmark: 86.6%

Based on 25 completed trials

Clinical Trials (123)

Showing 20 of 20 trials
NCT05578326Phase 2Recruiting

Study of Trilaciclib and Lurbinectidin

NCT04342429Not ApplicableRecruitingPrimary

Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer

NCT07625644Phase 3Recruiting

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

NCT04152499Phase 1Active Not Recruiting

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

NCT06449209Phase 2Active Not Recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

NCT07218146Phase 3RecruitingPrimary

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

NCT05091567Phase 3Active Not RecruitingPrimary

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

NCT07005128Phase 3Active Not RecruitingPrimary

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

NCT07803848Phase 2RecruitingPrimary

Study to Confirm Efficacy and Feasibility of Tarlatamab Treatment in Patients With Extensive Stage Small-cell Lung Cancer With Poor Performance Status

NCT06478043Phase 2CompletedPrimary

A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for SCLC

NCT07623369Phase 1Recruiting

A First-in-Human Study of HH160 in Participants With Advanced or Metastatic Solid Tumors

NCT03728361Phase 2Completed

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

NCT05552846Not ApplicableRecruitingPrimary

Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapy

NCT07155200Phase 1RecruitingPrimary

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

NCT06242470Phase 1Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT07468656Not Yet RecruitingPrimary

SCLC Tarlatamab Blood Collection

NCT07545954Phase 1RecruitingPrimary

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

NCT06486428Active Not RecruitingPrimary

Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

NCT05957510Phase 2Active Not RecruitingPrimary

Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment

NCT05616624Phase 1Terminated

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

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