Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

7.9%

3 terminated out of 38 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

33%

1 of 3 completed with results

Key Signals

1 with results50% success

Data Visualizations

Phase Distribution

34Total
Not Applicable (1)
P 1 (12)
P 2 (20)
P 3 (1)

Trial Status

Recruiting12
Not Yet Recruiting8
Unknown8
Active Not Recruiting4
Completed3
Terminated3

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (38)

Showing 20 of 20 trials
NCT07227597Phase 1RecruitingPrimary

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

NCT05384015Phase 2Active Not RecruitingPrimary

Study of Pembrolizumab, Lenvatinib and Chemotherapy Combination in First Line Extensive-stage Small Cell Lung Cancer

NCT07545954Phase 1Not Yet Recruiting

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

NCT03923270Phase 1Active Not RecruitingPrimary

Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer

NCT05680922Phase 1Active Not RecruitingPrimary

DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

NCT06610734Phase 2RecruitingPrimary

Multicenter, Phase II Randomized Controlled Study of Adebrelimab Combined With Chemotherapy and Concurrent Low-Dose Radiotherapy (LDRT) for the Treatment of Extensive-Stage Small Cell Lung Cancer (SCLC)

NCT06939036Phase 1TerminatedPrimary

Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 )

NCT07139990Phase 1RecruitingPrimary

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

NCT05703971Phase 1RecruitingPrimary

Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients

NCT05856695Phase 2Active Not RecruitingPrimary

Durvalumab Plus Etoposide-free Chemotherapy in First-line Treatment of Extensive-disease Small-sell Lung Cancer (SCLC)

NCT06982287Not Yet RecruitingPrimary

A Retrospective Real-World Study on the Efficacy and Safety of Anlotinib Hydrochloride Combined With Immunotherapy Maintenance Therapy Following Standard Chemoimmunotherapy for ES-SCLC (ALTER-L059)

NCT06954246Phase 3RecruitingPrimary

A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

NCT07022301Phase 2Not Yet RecruitingPrimary

Sintilimab Plus Anlotinib as Second or Further-line Therapy for ES-SCLC Who Have Progressed After Anti-PD-1/L1 Therapy

NCT06429696Phase 2RecruitingPrimary

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

NCT06348797Phase 1RecruitingPrimary

Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC

NCT06030258Phase 1RecruitingPrimary

IN10018 Combination Therapy in Treatment-naïve ES-SCLC

NCT06851819Phase 2Not Yet RecruitingPrimary

Tislelizumab in Combination with Chemotherapy ± Radiotherapy for Extensive-Stage Oligometastatic Small Cell Lung Cancer.

NCT06825208Not Yet RecruitingPrimary

Etoposide Plus Benmelstobart Followed by Maintenance Therapy of Benmelstobart Plus Anlotinib in First-line Treatment of Elderly Patients with Extensive Stage Small Cell Lung Cancer: a Single-arm, Prospective Trial

NCT05745350Phase 2RecruitingPrimary

First Line Pembrolizumab, Plinabulin Plus Etoposide and Platinum (EP) for ES-SCLC

NCT04462276Phase 2CompletedPrimary

Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease

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