Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

0.0%

0 terminated out of 17 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

29%

5 trials in Phase 3/4

Results Transparency

33%

2 of 6 completed with results

Key Signals

2 with results100% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (3)
P 2 (4)
P 3 (5)

Trial Status

Completed6
Recruiting5
Active Not Recruiting4
Unknown2

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT07047144Phase 2Recruiting

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

NCT06877689UnknownPrimary

EAP of Apitegromab for Patients With Spinal Muscular Atrophy

NCT05337553Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

NCT03461289Phase 3CompletedPrimary

Single-Dose Gene Replacement Therapy Clinical Trial for Participants With Spinal Muscular Atrophy Type 1

NCT05156320Phase 3Completed

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam

NCT05102916RecruitingPrimary

Swiss Registry for Neuromuscular Disorders

NCT07321990RecruitingPrimary

Study of the Reproducibility of the French Version of the Modified SMAFRS Scale

NCT06300996Not ApplicableActive Not Recruiting

Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb

NCT05626855Phase 3Active Not Recruiting

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab

NCT04042025Phase 3Active Not Recruiting

Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi

NCT03921528Phase 2Completed

An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy

NCT04292574Recruiting

UK SMA Patient Registry

NCT06322654Not ApplicableRecruitingPrimary

A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients

NCT04825119Unknown

Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen

NCT02941328Phase 2Completed

SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4

NCT01984957Not ApplicableCompleted

Differential Study of Muscle Transcriptome

NCT00774423Phase 2CompletedPrimary

Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA)

Showing all 17 trials

Research Network

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